TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T34429	Neuronal acetylcholine receptor alpha-7	D09ADT	ABT-418	Discontinued in Phase 2	119380	C9H14N2O	166.22	CC1=NOC(=C1)[C@@H]2CCCN2C	EC50 = 264000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B0WE9G	5-Methyl-4,13-diazatricyclo[8.2.1.02,7]trideca-2(7),3,5-triene	Investigative	44389116	C12H16N2	188.27	CC1=CC2=C(C=N1)C3CCC(N3)CC2	Ki ~ 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B1G8UQ	3-Cyclopropyl-3-(dimethylamino)propyl dimethylcarbamate	Investigative	44570101	C11H22N2O2	214.3	CN(C)C(CCOC(=O)N(C)C)C1CC1	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B2IVQ3	O-3-(Dimethylamino)butyl dimethylcarbamothioate	Investigative	44570056	C9H20N2OS	204.34	CC(CCOC(=S)N(C)C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B43EBR	3-(Dimethylamino)butyl 3-phenylpropylcarbamate	Investigative	44570057	C16H26N2O2	278.39	CC(CCOC(=O)NCCCC1=CC=CC=C1)N(C)C	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B5D3EM	3-(Dimethylamino)butyl 3-methylazetidine-1-carboxylate;oxalic acid	Investigative	49859909	C13H24N2O6	304.34	CC1CN(C1)C(=O)OCCC(C)N(C)C.C(=O)(C(=O)O)O	EC50 > 316227.77 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B71WQT	3-(Dimethylamino)-4-hydroxybutyl dimethylcarbamate	Investigative	44570100	C9H20N2O3	204.27	CN(C)C(CCOC(=O)N(C)C)CO	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	B90HMU	5-(Dimethylamino)-N-methylhex-2-enamide	Investigative	44570054	C9H18N2O	170.25	CC(C/C=C/C(=O)NC)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BD7CI3	3-(Dimethylamino)butyl carbamate	Investigative	44570009	C7H16N2O2	160.21	CC(CCOC(=O)N)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BDJU61	3-(Dimethylamino)-3-(thiophen-3-yl)propyl dimethylcarbamate	Investigative	44570102	C12H20N2O2S	256.37	CN(C)C(CCOC(=O)N(C)C)C1=CSC=C1	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BFK97P	3-(Dimethylamino)butyl methyl(phenyl)carbamate	Investigative	44570105	C14H22N2O2	250.34	CC(CCOC(=O)N(C)C1=CC=CC=C1)N(C)C	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BHZS95	3-(Dimethylamino)butyl 2-hydroxyethyl(methyl)carbamate	Investigative	44570104	C10H22N2O3	218.29	CC(CCOC(=O)N(C)CCO)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BI93PA	7-Methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h]isoquinoline	Investigative	10219887	C12H16N2O	204.27	COC1=NC=C2C3C(CCC2=C1)CCN3	EC50 > 300000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BIL2T5	3-(Dimethylamino)butyl benzyl(methyl)carbamate	Investigative	44570008	C15H24N2O2	264.36	CC(CCOC(=O)N(C)CC1=CC=CC=C1)N(C)C	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BJ1P2K	1-(3-(Dimethylamino)butyl)-3-phenylurea	Investigative	44570099	C13H21N3O	235.33	CC(CCNC(=O)NC1=CC=CC=C1)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BKT2W1	Desformylflustrabromine-B	Investigative	10471289	C16H21BrN2	321.25	CC(=CCN1C=C(C2=C1C=C(C=C2)Br)CCNC)C	IC50 = 209000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BKY57C	5-(Dimethylamino)-N,N-dimethylhex-2-enamide	Investigative	44570055	C10H20N2O	184.28	CC(C/C=C/C(=O)N(C)C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BMT2L8	3-(Dimethylamino)butyl ethylcarbamate	Investigative	44570010	C9H20N2O2	188.27	CCNC(=O)OCCC(C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BN07RM	3-(3-(Dimethylamino)butyl)-1,1-dimethylurea	Investigative	44570098	C9H21N3O	187.28	CC(CCNC(=O)N(C)C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BRB3Z9	S-3-(Dimethylamino)butyl dimethylcarbamothioate	Investigative	44570097	C9H20N2OS	204.34	CC(CCSC(=O)N(C)C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BS35CH	3-(Dimethylamino)butyl 4-chlorophenyl(methyl)carbamate	Investigative	44570006	C14H21ClN2O2	284.78	CC(CCOC(=O)N(C)C1=CC=C(C=C1)Cl)N(C)C	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BT5V6B	3-(Dimethylamino)-3-phenylpropyl dimethylcarbamate	Investigative	44570103	C14H22N2O2	250.34	CN(C)C(CCOC(=O)N(C)C)C1=CC=CC=C1	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BT8P5K	3-Nitrobenzoic acid [(2S)-1-methylpyrrolidine-2-yl]methyl ester	Investigative	73356479	C13H16N2O4	264.28	CN1CCC[C@H]1COC(=O)C2=CC(=CC=C2)[N+](=O)[O-]	Ki = 232000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BTW7M6	3-(Dimethylamino)butyl propylcarbamate	Investigative	44570011	C10H22N2O2	202.29	CCCNC(=O)OCCC(C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BU02KL	3-(Dimethylamino)butyl 4-cyanophenyl(methyl)carbamate	Investigative	44570007	C15H21N3O2	275.35	CC(CCOC(=O)N(C)C1=CC=C(C=C1)C#N)N(C)C	Ki = 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BU43PR	5-(Dimethylamino)-N,N-dimethylhexanamide	Investigative	44570053	C10H22N2O	186.29	CC(CCCC(=O)N(C)C)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	BUK47Y	3-(Dimethylamino)butyl 2-hydroxyethylcarbamate	Investigative	44570012	C9H20N2O3	204.27	CC(CCOC(=O)NCCO)N(C)C	Ki > 1000000 nM	Non binder
T34429	Neuronal acetylcholine receptor alpha-7	D00EJS	5-hydroxyindole	Investigative	16054	C8H7NO	133.15	C1=CC2=C(C=CN2)C=C1O	EC50 = 1000000 nM	Non binder