TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T29144 Arginase 1 B4CBL2 (2S)-2-Amino-6-borono-2-(2-piperidin-1-ylethyl)hexanoic acid Investigative 68064421 C13H27BN2O4 286.18 B(CCCC[C@](CCN1CCCCC1)(C(=O)O)N)(O)O IC50 > 300000 nM Non binder T29144 Arginase 2 B4CBL2 (2S)-2-Amino-6-borono-2-(2-piperidin-1-ylethyl)hexanoic acid Investigative 68064421 C13H27BN2O4 286.18 B(CCCC[C@](CCN1CCCCC1)(C(=O)O)N)(O)O IC50 > 300000 nM Non binder T29144 Arginase 1 B59HUF Chembl4238387 Investigative 145983954 C11H13N3O4 251.24 CC(=O)OC(C1=CC=C(C=C1)N=C(N)N)C(=O)O Ki = 382000 nM Non binder T29144 Arginase 2 B59HUF Chembl4238387 Investigative 145983954 C11H13N3O4 251.24 CC(=O)OC(C1=CC=C(C=C1)N=C(N)N)C(=O)O Ki = 437000 nM Non binder T29144 Arginase 1 B7W2YB 2-Amino-L-histidine Investigative 12071049 C6H10N4O2 170.17 C1=C(NC(=N1)N)C[C@@H](C(=O)O)N Ki = 300000 nM Non binder T29144 Arginase 1 BJ26OE 1H-Imidazol-2-amine Investigative 82140 C3H5N3 83.09 C1=CN=C(N1)N Ki = 3600000 nM Non binder T29144 Arginase 1 BJA98Z Chembl4250607 Investigative 145983883 C9H10FN3O2 211.19 C1=CC(=CC=C1C(C(=O)O)F)N=C(N)N Ki = 275000 nM Non binder T29144 Arginase 2 BJA98Z Chembl4250607 Investigative 145983883 C9H10FN3O2 211.19 C1=CC(=CC=C1C(C(=O)O)F)N=C(N)N Ki = 322000 nM Non binder T29144 Arginase 1 BM5S9V (S)-2-Amino-5-(imidazol-2-ylamino)pentanoic acid Investigative 46237587 C8H14N4O2 198.22 C1=CN=C(N1)NCCC[C@@H](C(=O)O)N Ki = 500000 nM Non binder T29144 Arginase 1 BTC1X8 (2s)-2-Amino-4-(2-Amino-1h-Imidazol-5-Yl)butanoic Acid Investigative 45259048 C7H12N4O2 184.2 C1=C(NC(=N1)N)CC[C@@H](C(=O)O)N Ki = 3000000 nM Non binder T29144 Arginase 1 BVL2M5 2-Amino-5-(2-aminoimidazol-4-yl)pentanoic acid Investigative 46237591 C8H14N4O2 198.22 C1=C(NC(=N1)N)CCCC(C(=O)O)N Ki > 80000000 nM Non binder