TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T23787 Renal carcinoma antigen NY-REN-56 B18JCP 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one Investigative 25142799 C17H12N2O 260.29 C1=CC=C2C(=C1)C=CC(=N2)/C=C/C(=O)C3=CC=NC=C3 IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 B7OT2I 4-Bromo-5-(morpholin-4-yl)-2-phenylpyridazin-3(2H)-one Investigative 733090 C14H14BrN3O2 336.18 C1COCCN1C2=C(C(=O)N(N=C2)C3=CC=CC=C3)Br IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 B7Y1SG 4-Bromo-5-(oxolan-2-ylmethylamino)-2-phenylpyridazin-3-one Investigative 76332026 C15H16BrN3O2 350.21 C1CC(OC1)CNC2=C(C(=O)N(N=C2)C3=CC=CC=C3)Br IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BAEV49 2-[(5-Bromo-6-oxo-1-phenylpyridazin-4-yl)amino]acetamide Investigative 76328355 C12H11BrN4O2 323.15 C1=CC=C(C=C1)N2C(=O)C(=C(C=N2)NCC(=O)N)Br IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BEP27Z 4-Bromo-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-2-phenylpyridazin-3-one Investigative 76317435 C15H14BrN3O2 348.19 C1C2(CN1C3=C(C(=O)N(N=C3)C4=CC=CC=C4)Br)COC2 IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BH5ZX1 2-(5-Bromo-6-oxo-1-phenylpyridazin-4-yl)-3,4-dihydro-1H-isoquinoline-5-carbonitrile Investigative 76310214 C20H15BrN4O 407.3 C1CN(CC2=C1C(=CC=C2)C#N)C3=C(C(=O)N(N=C3)C4=CC=CC=C4)Br IC50 > 500000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BLO24N 5-(4-Acetyl-5-methyltriazol-1-yl)-4-bromo-2-[[4-[2-(dimethylamino)ethylamino]phenyl]methyl]pyridazin-3-one Investigative 76328354 C20H24BrN7O2 474.4 CC1=C(N=NN1C2=C(C(=O)N(N=C2)CC3=CC=C(C=C3)NCCN(C)C)Br)C(=O)C IC50 > 500000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BMK15C 3H-Benzo[e]indol-2-yl(pyridin-4-yl)methanone Investigative 53374134 C18H12N2O 272.3 C1=CC=C2C(=C1)C=CC3=C2C=C(N3)C(=O)C4=CC=NC=C4 IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BO3N2L 5-(4-Acetyl-5-methyltriazol-1-yl)-2-phenyl-4-propan-2-ylpyridazin-3-one Investigative 76321168 C18H19N5O2 337.4 CC1=C(N=NN1C2=C(C(=O)N(N=C2)C3=CC=CC=C3)C(C)C)C(=O)C IC50 > 500000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BO4UH1 5-(4-Acetyl-5-methyltriazol-1-yl)-4-ethoxy-2-phenylpyridazin-3-one Investigative 76328357 C17H17N5O3 339.3 CCOC1=C(C=NN(C1=O)C2=CC=CC=C2)N3C(=C(N=N3)C(=O)C)C IC50 > 1000000 nM Non binder T23787 Renal carcinoma antigen NY-REN-56 BQ5DZ0 5-(4-Acetyl-5-methyltriazol-1-yl)-2-benzylpyridazin-3-one Investigative 76335630 C16H15N5O2 309.32 CC1=C(N=NN1C2=CC(=O)N(N=C2)CC3=CC=CC=C3)C(=O)C IC50 > 10000000 nM Non binder