TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T22976	Thymidine kinase 2	D07XSN	Cytarabine	Approved	6253	C9H13N3O5	243.22	C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O	IC50 > 1000000 nM	Non binder
T22976	Thymidine kinase 2	B05NKD	9-(2''-O-Pentanoyl-beta-D-arabinofuranosyl)guanine	Investigative	136118006	C15H21N5O6	367.36	CCCCC(=O)O[C@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	B12RXE	1-(2''-N-Nonylcarboxamido-2''-deoxy-beta-D-arabinofuranosyl)thymine	Investigative	44437455	C20H33N3O6	411.5	CCCCCCCCCC(=O)N[C@H]1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C)CO)O	IC50 = 480000 nM	Non binder
T22976	Thymidine kinase 2	B1JSK4	N3-Octyl-1-(2''-O-octyl-beta-D-arabinofuranosyl)thymine	Investigative	44437454	C26H46N2O6	482.7	CCCCCCCCN1C(=O)C(=CN(C1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)OCCCCCCCC)C	IC50 > 1000000 nM	Non binder
T22976	Thymidine kinase 2	B6L9RS	1-(2''-O-Octyl-beta-D-arabinofuranosyl)cytosine	Investigative	44437480	C18H29N3O6	383.4	CCCCCCCCC(=O)O[C@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O	IC50 > 1000000 nM	Non binder
T22976	Thymidine kinase 2	B76DEQ	Chembl285105	Investigative	22489180	C17H20N2O6	348.3	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)OCC3=CC=CC=C3	IC50 = 801000 nM	Non binder
T22976	Thymidine kinase 2	BG76ZV	9-beta-d-Arabinofuranosylguanine	Investigative	135499520	C10H13N5O5	283.24	C1=NC2=C(N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N=C(NC2=O)N	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	BGV09H	4-Amino-1-(4-hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one	Investigative	90663608	C17H29N3O5	355.4	CCCCCCCCO[C@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O	IC50 > 1000000 nM	Non binder
T22976	Thymidine kinase 2	BHSJ53	3'-[3-[3-(Trifluoromethyl)-4-chlorophenyl]thioureido]-5'-O-trityl-3'-deoxythymidine	Investigative	46197226	C37H32ClF3N4O4S	721.2	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)NC(=S)NC6=CC(=C(C=C6)Cl)C(F)(F)F	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	BJS65D	Spongothymidine	Investigative	65049	C10H14N2O6	258.23	CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O	IC50 = 285000 nM	Non binder
T22976	Thymidine kinase 2	BKO84H	Pentanoic acid 4-hydroxy-5-hydroxymethyl-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester	Investigative	491808	C15H22N2O7	342.34	CCCCC(=O)O[C@H]1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C)CO)O	IC50 > 1000000 nM	Non binder
T22976	Thymidine kinase 2	BL7Q2N	1-(3-Benzyloxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione	Investigative	491811	C17H20N2O6	348.3	CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)OCC3=CC=CC=C3	IC50 = 801000 nM	Non binder
T22976	Thymidine kinase 2	BORX53	N2-Octanoyl-9-(2''-O-octanoyl-beta-D-arabinofuranosyl)guanine	Investigative	136118007	C26H41N5O7	535.6	CCCCCCCC(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)OC(=O)CCCCCCC	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	BP8O1M	9-(2''-O-Octanoyl-beta-D-arabinofuranosyl)guanine	Investigative	136118008	C18H27N5O6	409.4	CCCCCCCC(=O)O[C@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	BR2AW6	N3-Octyl-1-(beta-D-arabinofuranosyl)thymine	Investigative	44437452	C18H30N2O6	370.4	CCCCCCCCN1C(=O)C(=CN(C1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O)C	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	BRO80M	1-[2''-O-(6-Aminohexanoyl)-beta-D-arabinofuranosyl]-5(E)-(2-bromovinyl)uracil	Investigative	44437478	C17H24BrN3O7	462.3	C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)OC(=O)CCCCCN)/C=C/Br	IC50 > 500000 nM	Non binder
T22976	Thymidine kinase 2	BY9U1V	Methoxy-acetic acid 2-[5-(2-bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-3-yl ester	Investigative	6476767	C14H17BrN2O8	421.2	COCC(=O)O[C@H]1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)/C=C/Br)CO)O	IC50 = 402000 nM	Non binder