TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T19531	Adenylate cyclase type 5	B18AHR	{Acetyl-[2-(6-amino-purin-9-yl)-ethyl]-amino}-acetic acid methyl ester	Investigative	44335303	C12H16N6O3	292.29	CC(=O)N(CCN1C=NC2=C(N=CN=C21)N)CC(=O)OC	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B1PK6F	(1S,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acid	Investigative	10945208	C12H15N5O2	261.279	C1C[C@H](C[C@H]1CC(=O)O)N2C=NC3=C(N=CN=C32)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B2CVB1	6-(6-Amino-purin-9-yl)-hexanoic acid	Investigative	44335158	C11H15N5O2	249.27	C1=NC(=C2C(=N1)N(C=N2)CCCCCC(=O)O)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B2P6UB	(1R,3S)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarboxylic acid hydroxyamide	Investigative	11832149	C11H12N6O2	260.25	C1[C@H](C=C[C@H]1N2C=NC3=C(N=CN=C32)N)C(=O)NO	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B2V5LO	[3-(6-Amino-purin-9-yl)-propylamino]-acetic acid methyl ester	Investigative	44335295	C11H16N6O2	264.28	COC(=O)CNCCCN1C=NC2=C(N=CN=C21)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B30KQN	6-(6-Amino-purin-9-yl)-hexanoic acid ethyl ester	Investigative	44335292	C13H19N5O2	277.32	CCOC(=O)CCCCCN1C=NC2=C(N=CN=C21)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B39GSM	5-(6-Aminopurin-9-yl)pentanoic acid	Investigative	253167	C10H13N5O2	235.24	C1=NC(=C2C(=N1)N(C=N2)CCCCC(=O)O)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B57AGD	[[(1R,4R)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetic acid	Investigative	44335691	C12H13N5O3	275.26	C1[C@H](C=C[C@@H]1OCC(=O)O)N2C=NC3=C(N=CN=C32)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B5MBU1	{Acetyl-[2-(6-amino-purin-9-yl)-ethyl]-amino}-acetic acid	Investigative	44335255	C11H14N6O3	278.27	CC(=O)N(CCN1C=NC2=C(N=CN=C21)N)CC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B76TIC	[3-(6-Amino-purin-9-yl)-propoxy]-acetic acid ethyl ester	Investigative	44335352	C12H17N5O3	279.3	CCOC(=O)COCCCN1C=NC2=C(N=CN=C21)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B7RY3W	[3-(6-Amino-purin-9-yl)-propylamino]-acetic acid	Investigative	44335305	C10H14N6O2	250.26	C1=NC(=C2C(=N1)N(C=N2)CCCNCC(=O)O)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B8Y6EV	(1R,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acid	Investigative	10858184	C12H13N5O2	259.26	C1[C@@H](C=C[C@@H]1N2C=NC3=C(N=CN=C32)N)CC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	B9TB3G	2-[Tert-Butoxycarbonyl[2-(6-amino-9H-purine-9-yl)ethyl]amino]acetohydroximic acid	Investigative	44335465	C14H21N7O4	351.36	CC(C)(C)OC(=O)N(CCN1C=NC2=C(N=CN=C21)N)CC(=O)NO	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BA1U0I	[[(1S,4S)-4-(6-Amino-9H-purine-9-yl)cyclopentyl]oxy]acetic acid	Investigative	44335698	C12H15N5O3	277.28	C1C[C@@H](C[C@H]1N2C=NC3=C(N=CN=C32)N)OCC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BF3IV4	{[2-(6-Amino-purin-9-yl)-ethyl]-methyl-amino}-acetic acid methyl ester	Investigative	44335279	C11H16N6O2	264.28	CN(CCN1C=NC2=C(N=CN=C21)N)CC(=O)OC	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BFY8G1	{[2-(6-Amino-purin-9-yl)-ethyl]-tert-butoxycarbonyl-amino}-acetic acid methyl ester	Investigative	10617830	C15H22N6O4	350.37	CC(C)(C)OC(=O)N(CCN1C=NC2=C(N=CN=C21)N)CC(=O)OC	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BGK8L4	[2-(6-Amino-purin-9-yl)-ethylamino]-acetic acid	Investigative	44335306	C9H12N6O2	236.23	C1=NC(=C2C(=N1)N(C=N2)CCNCC(=O)O)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BH31MA	{[3-(6-Amino-purin-9-yl)-propyl]-tert-butoxycarbonyl-amino}-acetic acid	Investigative	44335432	C15H22N6O4	350.37	CC(C)(C)OC(=O)N(CCCN1C=NC2=C(N=CN=C21)N)CC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BIJ3M1	6-Amino-9H-purine-9-heptanehydroximic acid	Investigative	44335277	C12H18N6O2	278.31	C1=NC(=C2C(=N1)N(C=N2)CCCCCCC(=O)NO)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BL9W2T	(1R,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acid	Investigative	11021644	C12H15N5O2	261.279	C1C[C@@H](C[C@@H]1CC(=O)O)N2C=NC3=C(N=CN=C32)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BLAE30	[(R)-3-((R)-6-Amino-purin-9-yl)-cyclopentyloxy]-acetic acid	Investigative	44335711	C12H15N5O3	277.28	C1C[C@H](C[C@H]1N2C=NC3=C(N=CN=C32)N)OCC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BLBT17	2-[2-(6-Amino-9H-purine-9-yl)ethylamino]acetohydroximic acid	Investigative	44335316	C9H13N7O2	251.25	C1=NC(=C2C(=N1)N(C=N2)CCNCC(=O)NO)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BMQ5I0	[2-(6-Amino-purin-9-yl)-ethylamino]-acetic acid methyl ester	Investigative	44335296	C10H14N6O2	250.26	COC(=O)CNCCN1C=NC2=C(N=CN=C21)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BO4M2K	[[(1R,4R)-4-(6-Amino-9H-purine-9-yl)cyclopentyl]oxy]acetic acid	Investigative	44335685	C12H15N5O3	277.28	C1C[C@H](C[C@@H]1N2C=NC3=C(N=CN=C32)N)OCC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BQ9W1O	{[2-(6-Amino-purin-9-yl)-ethyl]-tert-butoxycarbonyl-amino}-acetic acid	Investigative	44335433	C14H20N6O4	336.35	CC(C)(C)OC(=O)N(CCN1C=NC2=C(N=CN=C21)N)CC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BQH24T	N-[2-(6-Amino-purin-9-yl)-ethyl]-N-hydroxycarbamoylmethyl-acetamide	Investigative	44335293	C11H15N7O3	293.28	CC(=O)N(CCN1C=NC2=C(N=CN=C21)N)CC(=O)NO	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BR2I1Y	6-Amino-9H-purine-9-propanehydroximic acid	Investigative	44335253	C8H10N6O2	222.2	C1=NC(=C2C(=N1)N(C=N2)CCC(=O)NO)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BSA1Y5	2-[Tert-Butoxycarbonyl[3-(6-amino-9H-purine-9-yl)propyl]amino]acetohydroximic acid	Investigative	44335308	C15H23N7O4	365.39	CC(C)(C)OC(=O)N(CCCN1C=NC2=C(N=CN=C21)N)CC(=O)NO	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BSW51R	7-(6-Amino-purin-9-yl)-heptanoic acid ethyl ester	Investigative	44335470	C14H21N5O2	291.35	CCOC(=O)CCCCCCN1C=NC2=C(N=CN=C21)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BU9KN3	(1R,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acid	Investigative	10912229	C12H13N5O2	259.26	C1[C@@H](C=C[C@H]1N2C=NC3=C(N=CN=C32)N)CC(=O)O	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BWPB65	6-Amino-9H-purine-9-valeric acid methyl ester	Investigative	44335291	C11H15N5O2	249.27	COC(=O)CCCCN1C=NC2=C(N=CN=C21)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BZ5Y1S	7-(6-Amino-purin-9-yl)-heptanoic acid	Investigative	259205	C12H17N5O2	263.3	C1=NC(=C2C(=N1)N(C=N2)CCCCCCC(=O)O)N	IC50 > 200000 nM	Non binder
T19531	Adenylate cyclase type 5	BZRP39	2-[3-(6-Amino-9H-purine-9-yl)propylamino]acetohydroximic acid	Investigative	44335304	C10H15N7O2	265.27	C1=NC(=C2C(=N1)N(C=N2)CCCNCC(=O)NO)N	IC50 > 200000 nM	Non binder