TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T18477	Heat shock protein 90 alpha	D02LMZ	ATPase	Phase 2	5957	C10H16N5O13P3	507.18	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N	IC50 = 861330 nM	Non binder
T18477	Heat shock protein 90 alpha	B13NYV	(4S)-4-(5-Ethyl-2,4-dihydroxyphenyl)-1-(3,4,5-trimethoxyphenyl)azetidin-2-one	Investigative	56659880	C20H23NO6	373.4	CCC1=CC(=C(C=C1O)O)[C@@H]2CC(=O)N2C3=CC(=C(C(=C3)OC)OC)OC	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	B21LQE	(4S)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-(2,4-dimethoxyphenyl)azetidin-2-one	Investigative	56670202	C19H19NO5	341.4	COC1=CC(=C(C=C1)[C@@H]2CC(=O)N2C3=CC4=C(C=C3)OCCO4)OC	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	B6H4IT	8-((2,4-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine	Investigative	11349446	C16H13Cl2N5S	378.3	C#CCCCN1C2=NC=NC(=C2N=C1SC3=C(C=C(C=C3)Cl)Cl)N	IC50 > 300000 nM	Non binder
T18477	Heat shock protein 90 alpha	B6W1LK	8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine	Investigative	11302159	C18H19N5S	337.4	CC1=CC(=C(C=C1)SC2=NC3=C(N=CN=C3N2CCCC#C)N)C	IC50 > 300000 nM	Non binder
T18477	Heat shock protein 90 alpha	B75NEQ	8-((2,5-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine	Investigative	11450570	C18H19N5S	337.4	CC1=CC(=C(C=C1)C)SC2=NC3=C(N=CN=C3N2CCCC#C)N	IC50 > 300000 nM	Non binder
T18477	Heat shock protein 90 alpha	B7QX1Z	9-(Pent-4-yn-1-yl)-8-((2,4,5-trichlorophenyl)thio)-9H-purin-6-amine	Investigative	11223683	C16H12Cl3N5S	412.7	C#CCCCN1C2=NC=NC(=C2N=C1SC3=CC(=C(C=C3Cl)Cl)Cl)N	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	B85PWC	8-(Mesitylthio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine	Investigative	71660550	C19H21N5S	351.5	CC1=CC(=C(C(=C1)C)SC2=NC3=C(N=CN=C3N2CCCC#C)N)C	IC50 > 500000 nM	Non binder
T18477	Heat shock protein 90 alpha	BBP83L	8-((3,5-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine	Investigative	11406285	C16H13Cl2N5S	378.3	C#CCCCN1C2=NC=NC(=C2N=C1SC3=CC(=CC(=C3)Cl)Cl)N	IC50 > 500000 nM	Non binder
T18477	Heat shock protein 90 alpha	BD7RK1	2-Chloro-9-methyl-9H-purin-6-amine	Investigative	145989	C6H6ClN5	183.6	CN1C=NC2=C(N=C(N=C21)Cl)N	IC50 > 1250000 nM	Non binder
T18477	Heat shock protein 90 alpha	BES3V8	8-((3,5-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine	Investigative	11336657	C18H19N5S	337.4	CC1=CC(=CC(=C1)SC2=NC3=C(N=CN=C3N2CCCC#C)N)C	IC50 > 300000 nM	Non binder
T18477	Heat shock protein 90 alpha	BJ8ZC2	Methyl 3-[(2-methoxyacetyl)amino]-1-(3-methylbutyl)-5-(6-methylhept-5-en-2-ylamino)pyrrolo[2,3-b]pyridine-2-carboxylate	Investigative	45162180	C25H38N4O4	458.6	CC(C)CCN1C(=C(C2=C1N=CC(=C2)NC(C)CCC=C(C)C)NC(=O)COC)C(=O)OC	IC50 = 308500 nM	Non binder
T18477	Heat shock protein 90 alpha	BKSW27	(4S)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-(2,5-dimethoxyphenyl)azetidin-2-one	Investigative	56683692	C19H19NO5	341.4	COC1=CC(=C(C=C1)OC)[C@@H]2CC(=O)N2C3=CC4=C(C=C3)OCCO4	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	BO5ZX2	8-[(2,4-Dimethylphenyl)sulfanyl]-3-Pent-4-Yn-1-Yl-3h-Purin-6-Amine	Investigative	136236968	C18H19N5S	337.4	CC1=CC(=C(C=C1)SC2=NC3=C(N2)C(=N)N=CN3CCCC#C)C	IC50 > 250000 nM	Non binder
T18477	Heat shock protein 90 alpha	BRW7Q8	(4S)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-(2,4-dihydroxyphenyl)azetidin-2-one	Investigative	56670203	C17H15NO5	313.3	C1COC2=C(O1)C=CC(=C2)N3[C@@H](CC3=O)C4=C(C=C(C=C4)O)O	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	BRXL80	(4S)-4-(5-Ethyl-2,4-dihydroxyphenyl)-1-(4-methoxyphenyl)azetidin-2-one	Investigative	56663339	C18H19NO4	313.3	CCC1=CC(=C(C=C1O)O)[C@@H]2CC(=O)N2C3=CC=C(C=C3)OC	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	BSVO31	(3R,4S)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-4-(5-ethyl-2,4-dihydroxyphenyl)-3-phenylazetidin-2-one	Investigative	56677032	C25H23NO5	417.5	CCC1=CC(=C(C=C1O)O)[C@@H]2[C@H](C(=O)N2C3=CC4=C(C=C3)OCCO4)C5=CC=CC=C5	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	BY49JK	4-[8-(2,4-Dimethylphenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136934958	C17H18N6S	338.4	CC1=CC(=C(C=C1)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N)C	IC50 > 250000 nM	Non binder
T18477	Heat shock protein 90 alpha	BZ1C5J	(4S)-1-(1,3-Benzodioxol-5-yl)-4-(5-ethyl-2,4-dihydroxyphenyl)azetidin-2-one	Investigative	56659879	C18H17NO5	327.3	CCC1=CC(=C(C=C1O)O)[C@@H]2CC(=O)N2C3=CC4=C(C=C3)OCO4	IC50 > 200000 nM	Non binder
T18477	Heat shock protein 90 alpha	BZ5C2G	4-[8-(2,4-Dichlorophenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile	Investigative	136934957	C15H12Cl2N6S	379.3	C1=CC(=C(C=C1Cl)Cl)SC2=NC3=C(N2)C(=N)N=CN3CCCC#N	IC50 > 500000 nM	Non binder