TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T15139 Phosphoglycerate dehydrogenase B6BVX1 FC=1C=C(C=CC=1)C(C(=S)N1Ccocc1)=O Investigative 130429942 C12H12FNO2S 253.29 C1COCCN1C(=S)C(=O)C2=CC(=CC=C2)F IC50 > 200000 nM Non binder T15139 Phosphoglycerate dehydrogenase B6G3SC 2-Morpholin-4-yl-1-(4-phenylphenyl)-2-sulfanylideneethanone Investigative 130430007 C18H17NO2S 311.4 C1COCCN1C(=S)C(=O)C2=CC=C(C=C2)C3=CC=CC=C3 IC50 > 200000 nM Non binder T15139 Phosphoglycerate dehydrogenase BGK57I BrC=1C=C(C=CC=1)C(C(=S)N1CCOCC1)=O Investigative 130429983 C12H12BrNO2S 314.2 C1COCCN1C(=S)C(=O)C2=CC(=CC=C2)Br IC50 > 200000 nM Non binder T15139 Phosphoglycerate dehydrogenase BL2FP4 [N+](=O)([O-])C1=C(C=CC=C1)C(C(=S)N1Ccocc1)=O Investigative 130429947 C12H12N2O4S 280.3 C1COCCN1C(=S)C(=O)C2=CC=CC=C2[N+](=O)[O-] IC50 > 200000 nM Non binder T15139 Phosphoglycerate dehydrogenase BTI1G5 FC1=C(C=CC=C1)C(C(=S)N1Ccocc1)=O Investigative 130429999 C12H12FNO2S 253.29 C1COCCN1C(=S)C(=O)C2=CC=CC=C2F IC50 > 200000 nM Non binder T15139 Phosphoglycerate dehydrogenase BU0S5T 1-(2-Iodophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone Investigative 130430025 C12H12INO2S 361.2 C1COCCN1C(=S)C(=O)C2=CC=CC=C2I IC50 > 200000 nM Non binder T15139 Phosphoglycerate dehydrogenase BU96VH 1-(3-Iodophenyl)-2-morpholin-4-yl-2-sulfanylideneethanone Investigative 130430011 C12H12INO2S 361.2 C1COCCN1C(=S)C(=O)C2=CC(=CC=C2)I IC50 > 200000 nM Non binder