TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T10265	Phosphodiesterase 4B	D0DF2M	PMID28870136-Compound-48	Patented	2153	C7H8N4O2	180.16	CN1C2=C(C(=O)N(C1=O)C)NC=N2	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B16QKI	Chembl4284046	Investigative	145992787	C16H16ClN5O4	377.78	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)OC)CC(=O)NC3=CC(=CC=C3)Cl	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B1M6DQ	Chembl4294138	Investigative	145994146	C20H25N5O4	399.4	CCOC1=NC2=C(N1CC(=O)NC3=CC=C(C=C3)C(C)C)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B43MWN	Chembl4276743	Investigative	145982932	C20H25N5O4	399.4	CC(C)(C)C1=CC=C(C=C1)NC(=O)CN2C3=C(N=C2OC)N(C(=O)N(C3=O)C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B4CMX3	Chembl4290575	Investigative	145988021	C21H27N5O4	413.5	CCOC1=NC2=C(N1CC(=O)NC3=CC=C(C=C3)C(C)(C)C)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B4D1VJ	Chembl4290979	Investigative	145989570	C18H20ClN5O4	405.8	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)OC)CCCC(=O)NC3=CC=C(C=C3)Cl	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B54YGB	Chembl4216676	Investigative	145974692	C21H26N6O6	458.5	CCOC1=NC2=C(N1CCCC(=O)N/N=C/C3=C(C=C(C=C3)OC)O)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B5VX6Q	Chembl4294370	Investigative	145993704	C21H27N5O4	413.5	CC(C)C1=CC=C(C=C1)NC(=O)CCCN2C3=C(N=C2OC)N(C(=O)N(C3=O)C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B72AOE	Chembl4213058	Investigative	145964412	C18H20N6O4	384.4	CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCCC(=O)N/N=C/C3=CC=CC=C3O	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	B8DCS3	3-(6-Chloro-4-methylpyridazin-3-yl)-2-isopropylpyrazolo[1,5-a]pyridine	Investigative	54583497	C15H15ClN4	286.76	CC1=CC(=NN=C1C2=C3C=CC=CN3N=C2C(C)C)Cl	IC50 > 400000 nM	Non binder
T10265	Phosphodiesterase 4B	BBK7U5	Chembl4280678	Investigative	145981946	C18H20ClN5O4	405.8	CCOC1=NC2=C(N1CC(=O)NCC3=CC=CC=C3Cl)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BD72GP	Chembl4279233	Investigative	145980304	C17H18ClN5O4	391.8	CCOC1=NC2=C(N1CC(=O)NC3=CC(=CC=C3)Cl)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BEN29A	Chembl4207716	Investigative	145975232	C21H26N6O5	442.5	CCOC1=NC2=C(N1CCCC(=O)N/N=C/C3=CC=CC=C3OC)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BK2EB7	Chembl4290814	Investigative	145987119	C18H20ClN5O4	405.8	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)OC)CCCC(=O)NC3=CC(=CC=C3)Cl	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BK6E5V	Chembl4280173	Investigative	145978996	C17H18ClN5O4	391.8	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)OC)CC(=O)NCC3=CC=CC=C3Cl	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BPZ74F	Chembl4218669	Investigative	145967554	C18H20N6O5	400.4	CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCCC(=O)N/N=C/C3=C(C=C(C=C3)O)O	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BSQ98G	Chembl4283794	Investigative	145992781	C19H22ClN5O4	419.9	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)OC)CCCC(=O)NCC3=CC=CC=C3Cl	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BVMI81	6-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-5-methylpyridazin-3(2H)-one	Investigative	54580520	C15H16N4O	268.31	CC1=CC(=O)NN=C1C2=C3C=CC=CN3N=C2C(C)C	IC50 > 400000 nM	Non binder
T10265	Phosphodiesterase 4B	BY7X9D	Chembl4287403	Investigative	145990687	C19H23N5O4	385.4	CC(C)C1=CC=C(C=C1)NC(=O)CN2C3=C(N=C2OC)N(C(=O)N(C3=O)C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BYS05X	Chembl4210386	Investigative	145964309	C25H27N7O4	489.5	CN1C2=C(C(=O)N(C1=O)C)N(C(=N2)NCC3=CC=CC=C3)CCCC(=O)N/N=C/C4=CC=CC=C4O	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	BZ43WY	Chembl4287148	Investigative	145990259	C17H18ClN5O4	391.8	CCOC1=NC2=C(N1CC(=O)NC3=CC=C(C=C3)Cl)C(=O)N(C(=O)N2C)C	IC50 > 200000 nM	Non binder
T10265	Phosphodiesterase 4B	D0D6MC	HC-030031	Investigative	1150897	C18H21N5O3	355.4	CC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C	IC50 > 200000 nM	Non binder