TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T08280 Trypanosoma Pyrophosphate-dependent phosphofructokinase BAW86C (2R,3S,4S,5R)-2-(Hydroxymethyl)-5-[(naphthalen-2-ylamino)methyl]oxolane-3,4-diol Investigative 90666782 C16H19NO4 289.33 C1=CC=C2C=C(C=CC2=C1)NC[C@@H]3[C@H]([C@@H]([C@H](O3)CO)O)O IC50 = 900000 nM Non binder T08280 Trypanosoma Pyrophosphate-dependent phosphofructokinase BM8L1O 2,5-Anhydro-1-deoxy-1-(3,4-dichlorobenzylamino)-D-mannitol Investigative 44585399 C13H17Cl2NO4 322.18 C1=CC(=C(C=C1CNC[C@@H]2[C@H]([C@@H]([C@H](O2)CO)O)O)Cl)Cl IC50 = 410000 nM Non binder T08280 Trypanosoma Pyrophosphate-dependent phosphofructokinase BMBA37 (2R,3S,4S,5R)-2-[(3,4-Dichloroanilino)methyl]-5-(hydroxymethyl)oxolane-3,4-diol Investigative 90666783 C12H15Cl2NO4 308.15 C1=CC(=C(C=C1NC[C@@H]2[C@H]([C@@H]([C@H](O2)CO)O)O)Cl)Cl IC50 = 410000 nM Non binder