TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T02653 HUMAN mineralocorticoid receptor B6I4DM (3R)-3-[1-(4-Fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide Investigative 72188915 C26H22FN5OS 471.6 CC(C)([C@H](C1=CC=CC=C1)C2=CC3=C(C=C2)N(N=C3)C4=CC=C(C=C4)F)C(=O)NC5=NN=CS5 EC50 > 5000000 nM Non binder T02653 HUMAN mineralocorticoid receptor BD4WL5 (3S)-3-[1-(4-Fluorophenyl)indazol-5-yl]-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide Investigative 72188914 C26H22FN5OS 471.6 CC(C)([C@@H](C1=CC=CC=C1)C2=CC3=C(C=C2)N(N=C3)C4=CC=C(C=C4)F)C(=O)NC5=NN=CS5 EC50 > 5000000 nM Non binder T02653 HUMAN mineralocorticoid receptor BWO9E2 Lecanindole B Investigative 44605898 C23H29NO2 351.5 C[C@]12CCC(=O)C([C@@]1(CC[C@@H]3[C@@]2(C4=C(C3)C5=CC=CC=C5N4)C)O)(C)C IC50 > 10000000 nM Non binder T02653 HUMAN mineralocorticoid receptor D0F1SS Lecanindole D Investigative 44605900 C23H31NO2 353.5 C[C@]12CC[C@H](C([C@@]1(CC[C@@H]3[C@@]2(C4=C(C3)C5=CC=CC=C5N4)C)O)(C)C)O IC50 > 3000000 nM Non binder