TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	D00QNV	VFEDEOUBYBLDKN-AAFJCEBUSA-N	Patented	12111409	C20H29N7O	383.5	CC[C@H](C(CC)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	D06GXM	XHPNYYOUZWOWNT-PYUWXLGESA-N	Patented	12111413	C22H33N7O	411.5	CC[C@H](C(C(C)(C)C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	B3E1PU	(3S)-2-Methyl-3-[[9-propan-2-yl-6-(pyridin-3-ylmethylamino)purin-2-yl]amino]pentan-2-ol	Investigative	11581762	C20H29N7O	383.5	CC[C@@H](C(C)(C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	B4XL5V	(3RS,4S)-4-{9-Isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-2,2-dimethyl-hexan-3-ol	Investigative	12111414	C22H33N7O	411.5	CC[C@@H](C(C(C)(C)C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	B5QSP2	(1R,3S,4S)-Methyl 3-(6-amino-9H-purin-9-yl)-4-hydroxycyclopentanecarboxylate	Investigative	44435670	C12H15N5O3	277.28	COC(=O)[C@@H]1C[C@@H]([C@H](C1)O)N2C=NC3=C(N=CN=C32)N	IC50 > 1000000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	B9SAO0	(3RS,4S)-4-{9-Isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-hexan-3-ol	Investigative	12111410	C20H29N7O	383.5	CC[C@@H](C(CC)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	BF9DQ5	(2R,3S)-3-((9-Isopropyl-6-((pyridin-3-ylmethyl)amino)-9H-purin-2-yl)amino)pentan-2-ol	Investigative	9842276	C19H27N7O	369.5	CC[C@@H]([C@@H](C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	BP32GX	(3R)-3-{9-Isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-2-methyl-pentan-2-ol	Investigative	11574520	C20H29N7O	383.5	CC[C@H](C(C)(C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	BPZV35	(3RS,4S)-4-{9-Isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-2-methyl-hexan-3-ol	Investigative	12111412	C21H31N7O	397.5	CC[C@@H](C(C(C)C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	BT9O4K	(2S,3R)-3-[[9-Propan-2-yl-6-(pyridin-3-ylmethylamino)purin-2-yl]amino]pentan-2-ol	Investigative	12111408	C19H27N7O	369.5	CC[C@H]([C@H](C)O)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CN=CC=C3	IC50 > 200000 nM	Non binder
T00645	HUMAN protein kinase cAMP-activated catalytic subunit alpha	BWA15V	4-[[6-[[(2R)-6-Amino-1-[[6-[[(2R)-1-[[(2R)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-6-oxohexyl]amino]-1-oxohexan-2-yl]amino]-6-oxohexyl]carbamoylamino]benzamide	Investigative	46882837	C38H67N15O7	846	C1=CC(=CC=C1C(=O)N)NC(=O)NCCCCCC(=O)N[C@H](CCCCN)C(=O)NCCCCCC(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N	IC50 = 240000 nM	Non binder