TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00602	HUMAN excitatory amino acid transporter 1	D07XHJ	TAN-950A	Terminated	131738	C6H8N2O4	172.14	C1=C(C(=O)NO1)CC(C(=O)O)N	IC50 = 270000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B0RA6L	(2S,4R)-4-(3-Hydroxy-3-oxopropyl)glutamic Acid	Investigative	24905705	C8H13NO6	219.19	C(CC(=O)O)[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B15TLQ	(2S,4R)-2-Amino-4-[3-oxo-3-(phenylmethoxyamino)propyl]pentanedioic acid	Investigative	71574834	C15H20N2O6	324.33	C1=CC=C(C=C1)CONC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B18NEI	(2S,4R)-2-Amino-4-[3-oxo-3-(prop-2-ynylamino)propyl]pentanedioic acid	Investigative	71574743	C11H16N2O5	256.25	C#CCNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B1AZY8	2-Amino-3-(3-hydroxy-3H-imidazol-4-yl)-propionic acid	Investigative	11062853	C6H9N3O3	171.15	C1=C(N(C=N1)O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B1ZYW7	(2S,4R)-2-Amino-4-(3-oxo-3-piperidin-1-ylpropyl)pentanedioic acid	Investigative	71574747	C13H22N2O5	286.32	C1CCN(CC1)C(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B26SCG	(2S)-2-Amino-3-[(4-tert-butylphenyl)sulfonylamino]butanedioic acid	Investigative	134135313	C14H20N2O6S	344.39	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B29CWA	Dihydrokainic acid	Investigative	107883	C10H17NO4	215.25	CC(C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O	IC50 > 3000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B2QAS9	(2S,4R)-2-Amino-4-(2-aminoethyl)pentanedioic acid	Investigative	71574839	C7H14N2O4	190.2	C(CN)[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B32HSY	Ethyl (1E)-N-(3-cyano-5-oxo-4,7-diphenyl-4,6,7,8-tetrahydrochromen-2-yl)methanimidate	Investigative	49782834	C25H22N2O3	398.5	CCO/C=N/C1=C(C(C2=C(O1)CC(CC2=O)C3=CC=CC=C3)C4=CC=CC=C4)C#N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B34BQD	(2S,4R)-2-Amino-4-[3-(diethylamino)-3-oxopropyl]pentanedioic acid	Investigative	71574746	C12H22N2O5	274.31	CCN(CC)C(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B3BU6R	(2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic acid;hydrochloride	Investigative	137643975	C12H14ClNO5	287.69	C1[C@H](CN[C@@H]1C(=O)O)OC2=CC=CC=C2C(=O)O.Cl	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B3I0VG	(2S,4S)-4-(Benzyloxymethyl)glutamic Acid	Investigative	24905652	C13H17NO5	267.28	C1=CC=C(C=C1)COC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 450000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B3KSN6	(4r)-4-{3-[Hydroxy(Methyl)amino]-3-Oxopropyl}-L-Glutamic Acid	Investigative	70789291	C9H16N2O6	248.23	CN(C(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O)O	IC50 > 3000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B5T3MR	2-Amino-3-(1-hydroxy-1H-imidazol-2-yl)-propionic acid	Investigative	11041159	C6H9N3O3	171.15	C1=CN(C(=N1)CC(C(=O)O)N)O	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B6NEY7	1,2,4-Butanetricarboxylic acid, 4-amino-, (2S,4S)-	Investigative	24905703	C7H11NO6	205.17	C([C@@H](CC(=O)O)C(=O)O)[C@@H](C(=O)O)N	Ki > 3000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B6RUM7	5-Methyl-1-hydroxy-alpha-amino-1H-imidazole-2-propionic acid	Investigative	10877814	C7H11N3O3	185.18	CC1=CN=C(N1O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B7D3CJ	(2S,4R)-2-Amino-4-(3-aminopropyl)pentanedioic acid	Investigative	71574840	C8H16N2O4	204.22	C(C[C@H](C[C@@H](C(=O)O)N)C(=O)O)CN	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B89TPO	(3S,5S)-2-Aza-bicyclo[2.2.1]heptane-3,5-dicarboxylic acid	Investigative	10419887	C8H11NO4	185.18	C1[C@@H](C2CC1N[C@@H]2C(=O)O)C(=O)O	Ki > 400000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B8KP9W	(2S)-2-Amino-3-[(4-methylsulfonylphenyl)sulfonylamino]butanedioic acid	Investigative	134152035	C11H14N2O8S2	366.4	CS(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	B9G3MI	(2S,4S)-4-(Hydroxymethyl)glutamic Acid	Investigative	24905651	C6H11NO5	177.16	C([C@@H](CO)C(=O)O)[C@@H](C(=O)O)N	IC50 = 3000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BAX6N3	(2S)-2-Amino-3-(4-phenyltriazol-1-yl)butanedioic acid	Investigative	134139698	C12H12N4O4	276.25	C1=CC=C(C=C1)C2=CN(N=N2)C([C@@H](C(=O)O)N)C(=O)O	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BB3QZ8	(4r)-4-[3-(Methylamino)-3-Oxopropyl]-L-Glutamic Acid	Investigative	24905647	C9H16N2O5	232.23	CNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BDC30V	(2S)-2-Amino-3-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]butanedioic acid	Investigative	134144947	C10H7F5N2O6S	378.23	C1(=C(C(=C(C(=C1F)F)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)F)F)F	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BE1JZ3	2-Amino-3-(2-hydroxy-2H-pyrazol-3-yl)-propionic acid	Investigative	10986716	C6H9N3O3	171.15	C1=C(N(N=C1)O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BE3T2U	5-Methyl-3-hydroxy-alpha-amino-3H-1,2,3-triazole-4-propionic acid	Investigative	10219727	C6H10N4O3	186.17	CC1=C(N(N=N1)O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BE91JP	(2S,4R)-2-Amino-4-[3-(hydroxyamino)-3-oxopropyl]pentanedioic acid	Investigative	71574838	C8H14N2O6	234.21	C(CC(=O)NO)[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BF5AP2	2-Amino-5-oxo-4,7-diphenyl-7,8-dihydro-4H-pyrano[3,2-c]pyran-3-carbonitrile	Investigative	70690647	C21H16N2O3	344.4	C1C(OC(=O)C2=C1OC(=C(C2C3=CC=CC=C3)C#N)N)C4=CC=CC=C4	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BF8R7M	(2S,4R)-4-(3-Amino-3-oxopropyl)glutamic acid	Investigative	24905646	C8H14N2O5	218.21	C(CC(=O)N)[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 = 3000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BG1FO9	(1R)-1-[(S)-2-Amino-3-oxo-3-hydroxypropyl]cyclopropane-1alpha,2alpha-dicarboxylic acid	Investigative	127030387	C8H11NO6	217.18	C1[C@H]([C@@]1(C[C@@H](C(=O)O)N)C(=O)O)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BI0T9N	(2S,4R)-4-(4-Carboxyphenoxy)pyrrolidine-2-carboxylic acid;hydrochloride	Investigative	90480101	C12H14ClNO5	287.69	C1[C@H](CN[C@@H]1C(=O)O)OC2=CC=C(C=C2)C(=O)O.Cl	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BJN14H	(2S,4R)-4-(3-Carboxyphenoxy)pyrrolidine-2-carboxylic acid;hydrochloride	Investigative	90480134	C12H14ClNO5	287.69	C1[C@H](CN[C@@H]1C(=O)O)OC2=CC=CC(=C2)C(=O)O.Cl	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BK5FU2	(1S)-1-[(S)-2-Amino-3-oxo-3-hydroxypropyl]cyclopropane-1beta,2beta-dicarboxylic acid	Investigative	127030386	C8H11NO6	217.18	C1[C@@H]([C@]1(C[C@@H](C(=O)O)N)C(=O)O)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BM7AH6	(2S,4R)-Azepane-2,4-dicarboxylic acid	Investigative	71574841	C8H13NO4	187.19	C1C[C@H](C[C@H](NC1)C(=O)O)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BODA53	(2S,4R)-4-(2,2-Diphenylethylamino-3-oxopropyl)glutamic acid	Investigative	24905650	C22H26N2O5	398.5	C1=CC=C(C=C1)C(CNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	Ki = 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BQ70XL	2-Methyl-3-hydroxy-alpha-amino-3H-imidazole-4-propionic acid	Investigative	10997729	C7H11N3O3	185.18	CC1=NC=C(N1O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BQH58J	(1R)-1-[(S)-2-Amino-3-oxo-3-hydroxypropyl]cyclopropane-1alpha,2beta-dicarboxylic acid	Investigative	127030385	C8H11NO6	217.18	C1[C@@H]([C@@]1(C[C@@H](C(=O)O)N)C(=O)O)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BQOF37	4-Methyl-2-hydroxy-alpha-amino-2H-pyrazole-3-propionic acid	Investigative	10954230	C7H11N3O3	185.18	CC1=C(N(N=C1)O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BRC80P	(2S)-2-Amino-3-benzamidobutanedioic acid	Investigative	134143016	C11H12N2O5	252.22	C1=CC=C(C=C1)C(=O)NC([C@@H](C(=O)O)N)C(=O)O	IC50 = 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BSFY13	(2S,4R)-4-(3-Propylamino-3-oxopropyl)glutamic acid	Investigative	24905648	C11H20N2O5	260.29	CCCNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 3000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BSXW15	(2S)-2-Amino-3-[(3-carboxyphenyl)sulfonylamino]butanedioic acid	Investigative	134147363	C11H12N2O8S	332.29	C1=CC(=CC(=C1)S(=O)(=O)NC([C@@H](C(=O)O)N)C(=O)O)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BT0P6J	(2S)-2-Amino-3-[benzenesulfonyl(methyl)amino]butanedioic acid	Investigative	134150446	C11H14N2O6S	302.31	CN(C([C@@H](C(=O)O)N)C(=O)O)S(=O)(=O)C1=CC=CC=C1	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BT5J8Q	5-Methyl-3-hydroxy-alpha-amino-3H-imidazole-4-propionic acid	Investigative	11063103	C7H11N3O3	185.18	CC1=C(N(C=N1)O)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BTHR53	2-Amino-5-oxo-4,7-diphenyl-4,6,7,8-tetrahydropyrano[3,2-c]pyridine-3-carbonitrile	Investigative	70688590	C21H17N3O2	343.4	C1C(NC(=O)C2=C1OC(=C(C2C3=CC=CC=C3)C#N)N)C4=CC=CC=C4	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BUP7Y0	(1S,2R)-1-[(2S)-2-Amino-2-carboxyethyl]cyclopropane-1,2-dicarboxylic acid	Investigative	127031290	C8H11NO6	217.18	C1[C@H]([C@]1(C[C@@H](C(=O)O)N)C(=O)O)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BVD32M	(2S,4R)-2-Amino-4-(3-anilino-3-oxopropyl)pentanedioic acid	Investigative	71574744	C14H18N2O5	294.3	C1=CC=C(C=C1)NC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 > 300000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BWD32T	(2S,4R)-4-(3-Benzylamino-3-oxopropyl)glutamic acid	Investigative	24905649	C15H20N2O5	308.33	C1=CC=C(C=C1)CNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	Ki = 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	BZ90TJ	(2S,4S)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic acid;hydrochloride	Investigative	137658224	C12H14ClNO5	287.69	C1[C@@H](CN[C@@H]1C(=O)O)OC2=CC=CC=C2C(=O)O.Cl	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	D03RGP	(R,S)-AMPA	Investigative	1221	C7H10N2O4	186.17	CC1=C(C(=O)NO1)CC(C(=O)O)N	IC50 > 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	D03UIR	(2S,4R)-4-(3-Methoxy-3-oxopropyl)glutamic Acid	Investigative	24905704	C9H15NO6	233.22	COC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O	IC50 = 1000000 nM	Non binder
T00602	HUMAN excitatory amino acid transporter 1	D0X3CF	HINOKININ	Investigative	442879	C20H18O6	354.4	C1[C@@H]([C@H](C(=O)O1)CC2=CC3=C(C=C2)OCO3)CC4=CC5=C(C=C4)OCO5	IC50 > 500000 nM	Non binder