TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00477	Serine Racemase	D0M8AB	Glycine	Approved	750	C2H5NO2	75.07	C(C(=O)O)N	Ki = 366000 nM	Non binder
T00477	Serine Racemase	B04GTU	4-Ethyl-5-methylthiophene-2-carboxylic acid	Investigative	2512481	C8H10O2S	170.23	CCC1=C(SC(=C1)C(=O)O)C	IC50 = 5723000 nM	Non binder
T00477	Serine Racemase	B08YNF	(S)-2-((S)-3-(1H-Imidazol-4-yl)-2-(3-phenylpropanamido)propanamido)-4-phenylbutanamide	Investigative	11575956	C25H29N5O3	447.5	C1=CC=C(C=C1)CC[C@@H](C(=O)N)NC(=O)[C@H](CC2=CN=CN2)NC(=O)CCC3=CC=CC=C3	Ki = 320000 nM	Non binder
T00477	Serine Racemase	B21NBQ	(2S,3R)-2-((S)-3-(1H-Imidazol-4-yl)-2-(3-phenylpropanamido)propanamido)-3-methylpentanamide	Investigative	11964443	C21H29N5O3	399.5	CCC(C)[C@@H](C(=O)N)NC(=O)[C@H](CC1=CN=CN1)NC(=O)CCC2=CC=CC=C2	Ki = 610000 nM	Non binder
T00477	Serine Racemase	B2F9OW	3-Thiophenecarboxylic acid	Investigative	6918	C5H4O2S	128.15	C1=CSC=C1C(=O)O	IC50 = 8213000 nM	Non binder
T00477	Serine Racemase	B3E8LI	5-Phenyl-1,3,4-oxadiazol-2-ol	Investigative	352208	C8H6N2O2	162.15	C1=CC=C(C=C1)C2=NNC(=O)O2	IC50 > 10000000 nM	Non binder
T00477	Serine Racemase	B4PXW2	2-[3-[3-(2-Hydroxyethylsulfanyl)-5-nitrophenyl]-2-oxopropoxy]acetic acid	Investigative	122190496	C13H15NO7S	329.33	C1=C(C=C(C=C1[N+](=O)[O-])SCCO)CC(=O)COCC(=O)O	Ki = 4500000 nM	Non binder
T00477	Serine Racemase	B9A5ON	Chembl4205674	Investigative	145978550	C20H22N2O5S	402.5	CC(=O)NC1=CC=C(C=C1)NC(=O)COC(=O)CCSC2=CC=CC=C2OC	IC50 = 836000 nM	Non binder
T00477	Serine Racemase	B9X3ZD	3-Hydroxycinnamic acid	Investigative	637541	C9H8O3	164.16	C1=CC(=CC(=C1)O)/C=C/C(=O)O	IC50 = 8386000 nM	Non binder
T00477	Serine Racemase	BDL05G	Benzoic acid	Investigative	243	C7H6O2	122.12	C1=CC=C(C=C1)C(=O)O	IC50 > 10000000 nM	Non binder
T00477	Serine Racemase	BF3CQ8	Crotonic acid	Investigative	637090	C4H6O2	86.09	C/C=C/C(=O)O	IC50 > 10000000 nM	Non binder
T00477	Serine Racemase	BGM2R3	5-Methyl-4-propylthiophene-2-carboxylic acid	Investigative	3686650	C9H12O2S	184.26	CCCC1=C(SC(=C1)C(=O)O)C	IC50 = 5159000 nM	Non binder
T00477	Serine Racemase	BH5S6D	4,5,6,7-Tetrahydrobenzo[b]thiophene-2-carboxylic acid	Investigative	2063443	C9H10O2S	182.24	C1CCC2=C(C1)C=C(S2)C(=O)O	IC50 = 5015000 nM	Non binder
T00477	Serine Racemase	BL0Q5S	3-Hydroxycoumarin	Investigative	13650	C9H6O3	162.14	C1=CC=C2C(=C1)C=C(C(=O)O2)O	IC50 > 10000000 nM	Non binder
T00477	Serine Racemase	BL53DU	Mesotartaric acid	Investigative	447315	C4H6O6	150.09	[C@@H]([C@@H](C(=O)O)O)(C(=O)O)O	IC50 = 2820000 nM	Non binder
T00477	Serine Racemase	BLK47B	Thiophen-2-ylsulfonylmethylcarbamic acid	Investigative	122190495	C6H7NO4S2	221.3	C1=CSC(=C1)S(=O)(=O)CNC(=O)O	Ki = 1500000 nM	Non binder
T00477	Serine Racemase	BRMJ25	5-(2-Methylphenyl)-3H-1,3,4-oxadiazol-2-one	Investigative	833670	C9H8N2O2	176.17	CC1=CC=CC=C1C2=NNC(=O)O2	IC50 > 5000000 nM	Non binder
T00477	Serine Racemase	BS8X1P	N-(4-Bromophenyl)-2-[[2-(4-fluorophenoxy)acetyl]amino]acetamide	Investigative	89717825	C16H14BrFN2O3	381.2	C1=CC(=CC=C1NC(=O)CNC(=O)COC2=CC=C(C=C2)F)Br	IC50 = 520000 nM	Non binder
T00477	Serine Racemase	BSH69I	5,6-Dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acid	Investigative	770980	C8H8O2S	168.21	C1CC2=C(C1)SC(=C2)C(=O)O	IC50 = 5282000 nM	Non binder
T00477	Serine Racemase	BSL75D	N-[(1,3-Dimethyl-2,4,6-trioxotetrahydro-5(2H)-pyrimidinylidene)methyl]aspartic acid	Investigative	2905941	C11H13N3O7	299.24	CN1C(=C(C(=O)N(C1=O)C)C=NC(CC(=O)O)C(=O)O)O	Ki = 1700000 nM	Non binder
T00477	Serine Racemase	BSVR94	3-(Carboxymethyl)-1-azabicyclo[2.2.2]octane-3-carboxylic acid	Investigative	11834812	C10H15NO4	213.23	C1CN2CCC1C(C2)(CC(=O)O)C(=O)O	Ki > 10000000 nM	Non binder
T00477	Serine Racemase	BVO82S	2-[[2-(4-Bromophenoxy)acetyl]amino]-N-(2,6-difluorophenyl)acetamide	Investigative	89717779	C16H13BrF2N2O3	399.19	C1=CC(=C(C(=C1)F)NC(=O)CNC(=O)COC2=CC=C(C=C2)Br)F	IC50 = 630000 nM	Non binder
T00477	Serine Racemase	BVU2F6	4-Ethyl-5-propylthiophene-2-carboxylic acid	Investigative	2113906	C10H14O2S	198.28	CCCC1=C(C=C(S1)C(=O)O)CC	IC50 > 10000000 nM	Non binder
T00477	Serine Racemase	BXL18Q	(2S)-2-[(4-Nitrophenyl)sulfonylamino]butanoic acid	Investigative	1105076	C10H12N2O6S	288.28	CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	Ki = 1500000 nM	Non binder
T00477	Serine Racemase	D08ZAO	Tricarballylic Acid	Investigative	14925	C6H8O6	176.12	C(C(CC(=O)O)C(=O)O)C(=O)O	Ki = 1300000 nM	Non binder