Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| HER2 --- CD221 | N-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | Drug Info |
| HER2 --- CD221 | 1-((trans)-4-morpholinocyclohexyl)-3-(2-(thiophen-2-ylmethyl)-1H-benzo[d]imidazol-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| HER2 --- CD221 | trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-3-chlorophenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | N-(4-(4-amino-1-(1'-(3-methoxypropyl)-1,4'-bipiperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | N-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-phenylacetamide | Drug Info |
| HER2 --- CD221 | 1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-phenethyl-1H-benzo[d]imidazol-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| HER2 --- CD221 | cis-N-(4-(4-amino-1-(4-(4-(3-methoxypropyl)piperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-fluorophenyl)-5,7-dimethylbenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | 1-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)-3-phenylurea | Drug Info |
| HER2 --- CD221 | 3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-6-yl)-1-((trans)-4-morpholinocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| HER2 --- CD221 | cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-7-chloro-5-methylbenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | N-(4-(4-amino-1-(1'-isopropyl-1,4'-bipiperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | 2-cyclohexyl-N-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)acetamide | Drug Info |
| HER2 --- CD221 | phenyl 3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenylcarbamate | Drug Info |
| HER2 --- CD221 | trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-3-methylphenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | 2-cyclopentyl-N-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)acetamide | Drug Info |
| HER2 --- CD221 | 2,6-difluoro-N-(3-(5-(2-(3-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | Drug Info |
| HER2 --- CD221 | trans-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-chlorophenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
| HER2 --- CD221 | 3-(2-(2-chlorobenzyl)-1H-benzo[d]imidazol-6-yl)-1-((trans)-4-morpholinocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | Drug Info |
| HER2 --- CD221 | trans-2-(4-(4-(4-amino-3-(4-(7-chlorobenzo[d]oxazol-2-ylamino)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)cyclohexyl)piperazin-1-yl)-N,N-dimethylacetamide | Drug Info |
| HER2 --- CD221 | 2,6-difluoro-N-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | Drug Info |
| HER2 --- CD221 | N-(3-(5-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-6-ylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-phenylacetamide | Drug Info |
| HER2 --- CD221 | SID103904421 | Drug Info |
| HER2 --- CD221 | trans-N-(4-(4-amino-1-(4-morpholinocyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-7-chlorobenzo[d]oxazol-2-amine | Drug Info |
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