Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| PPAR gamma --- PPAR delta | 2-{4-[2-(1,2,3,4-Tetrahydro-quinolin-7-yloxy)-ethoxy]-benzyl}-malonic acid dimethyl ester | Drug Info |
| HDAC1 --- HDAC2 | 4-(3-(4-(Cyclopentyloxy)-3-methoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
| EGFR3 --- VEGFR1 | N*6*-Imidazol-1-yl-N*4*-(1H-indol-5-yl)-N*6*-(3-phenyl-propyl)-thieno[3,2-d]pyrimidine-4,6-diamine | Drug Info |
| PPAR gamma --- PPAR delta | 2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-6-yloxy)acetic acid | Drug Info |
| HDAC1 --- HDAC2 | 7-Methoxy-benzofuran-2-carboxylic acid (6-hydroxycarbamoyl-hexyl)-amide | Drug Info |
| Erbeta --- ER | (2S,3R)-2-{4-[2-(2-Aza-bicyclo[2.2.2]oct-2-yl)-ethoxy]-phenyl}-3-(4-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 5-chloro-2-(3-(5-methoxy-4-methyl-1H-indol-1-ylsulfonyl)benzamido)benzoic acid | Drug Info |
| HDAC1 --- HDAC2 | 2-Oxo-nonanedioic acid 1-methylamide 9-[(4-phenyl-thiazol-2-yl)-amide] | Drug Info |
| Erbeta --- ER | (S)-9a-butyl-1-fluoro-6-(trifluoromethyl)-8,9,9a,10-tetrahydroindeno[2,1-e]indazol-7(3H)-one | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-(((3-(benzo[d][1,3]dioxol-5-yloxy)propyl)(benzo[d]oxazol-2-yl)amino)methyl)phenoxy)butanoic acid | Drug Info |
| HDAC1 --- HDAC2 | N-(4-amino-biphenyl-3-yl)-4-[(3,4-dimethoxy-phenylamino)-methyl]-benzamide | Drug Info |
| Erbeta --- ER | 4-{(E)-1-[4-(2-Diethylamino-ethoxy)-phenyl]-hexadec-1-enyl}-phenol | Drug Info |
| PPAR gamma --- PPAR delta | (S)-2-ethoxy-3-(1-((5-methyl-2-phenyloxazol-4-yl)methyl)-1H-indol-4-yl)propanoic acid | Drug Info |
| HDAC1 --- HDAC2 | N-(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzyl)morpholine-4-carboxamide | Drug Info |
| Erbeta --- ER | (2S,3R)-2-{4-[2-(2,6-Dimethyl-piperidin-1-yl)-ethoxy]-phenyl}-3-(3-hydroxy-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | (R)-3-(4-(3-(1-(5-chloro-3-methylbenzo[b]thiophene-2-carboxamido)ethyl)-5-fluorophenoxy)-2-ethylphenyl)propanoic acid | Drug Info |
| HDAC1 --- HDAC4 | cyclo(-L-Am7(S2Py)-L-A1in-L-Ala-D-Pro-) | Drug Info |
| Erbeta --- ER | 17alpha-[2-Cyano-2-(ethoxycarbonyl)-1,3-dihydro-2H-inden-5-yl]-estradiol | Drug Info |
| PPAR gamma --- PPAR delta | (R)-3-(4-(3-(4-ethyl-2-(thiazol-4-yl)phenoxy)butoxy)-2-methylphenyl)propanoic acid | Drug Info |
| HER2 --- CD221 | 1-(3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenyl)-3-phenylurea | Drug Info |
| Erbeta --- ER | 1-[4-(1-Methyl-piperidin-4-yl)-phenyl]-2-phenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(3-(4-bromo-1H-indol-1-ylsulfonyl)benzamido)-5-methylbenzoic acid | Drug Info |
| IKKbeta --- JAK2 | (4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)phenyl)(4-(dimethylamino)piperidin-1-yl)methanone | Drug Info |
| Erbeta --- ER | (2S,3R)-3-(4-Hydroxy-phenyl)-2-(4-piperidin-1-ylmethyl-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(2-(1-(4-cyclohexylbutyl)-3-(2-methoxyphenyl)ureido)ethyl)phenylthio)-2-methylpropanoic acid | Drug Info |
| JNK1 --- JNK3 | 3-(6-(2-chlorophenylamino)-1H-indazol-3-yl)-5-(4-(dimethylamino)butanamido)benzoic acid | Drug Info |
| Erbeta --- ER | (2R,3R,4S)-5-Fluoro-3-(4-hydroxy-phenyl)-4-methyl-2-{4-[(S)-2-((R)-2-methyl-pyrrolidin-1-yl)-propoxy]-phenyl}-chroman-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(3-(2-chloro-4-(4-fluorophenoxy)phenoxy)propoxy)phenoxy)-2-methylpropanoic acid | Drug Info |
| JNK1 --- JNK3 | methyl 3-(2-(naphthalen-1-yl)acetamido)thiophene-2-carboxylate | Drug Info |
| Erbeta --- ER | 3-hydroxy-8,10-dimethyl-6H-benzo[c]chromen-6-one | Drug Info |
| PPAR gamma --- PPAR delta | 2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-phenoxy)-propoxy]-2,3-dihydro-benzofuran-2-carboxylic acid | Drug Info |
| JNK1 --- JNK3 | SID103905197 | Drug Info |
| Erbeta --- ER | 8-(2,2-dimethylpropyl)naringenin | Drug Info |
| PPAR gamma --- PPAR delta | (Z)-2-(2-methyl-4-(6-phenyl-4-(quinolin-3-yl)hex-2-en-5-ynyloxy)phenoxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | N-(2-(5-methyl-1H-1,2,4-triazol-3-yl)thiophen-3-yl)-2-(naphthalen-1-yl)acetamide | Drug Info |
| Erbeta --- ER | 2-(5-bromo-6-hydroxynaphthalen-1-yl)benzo[d]oxazol-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(2-(pent-2-ynyloxy)-4-((3-(trifluoromethyl)phenoxy)methyl)phenylthio)-5,6,7,8-tetrahydronaphthalen-1-yloxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | 5-(difluoromethyl)-N-(3-methyl-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)phenyl)furan-2-carboxamide | Drug Info |
| Erbeta --- ER | (4-{6-Hydroxy-3-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-benzo[b]thiophen-2-yl}-phenyl)-phosphonic acid diethyl ester | Drug Info |
| PPAR gamma --- PPAR delta | 2-(2-methyl-4-(3-(2-propyl-4-(trifluoromethyl)phenoxy)propoxy)phenoxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | N-(4-(methylsulfonyl)benzyl)-4-amino-5-(2-cyanovinyl)-6-ethoxypicolinamide | Drug Info |
| Erbeta --- ER | (2S,3R)-3-(4-Hydroxy-phenyl)-2-(4-piperidin-4-yl-phenyl)-2,3-dihydro-benzo[1,4]oxathiin-6-ol | Drug Info |
| JNK1 --- JNK3 | 2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-yl)acetamide | Drug Info |
| Erbeta --- ER | (S)(-)-6-bromo-9a-butyl-8,9,9a,10-tetrahydro-3H-1,2,3-triaza-cyclopenta[a]fluoren-7-one | Drug Info |
| JNK1 --- JNK3 | N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-styrylpicolinamide | Drug Info |
| PPAR gamma --- PPAR delta | 3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-propionic acid | Drug Info |
| Erbeta --- ER | 3-hydroxy-4,7,10-trimethyl-6H-benzo[c]chromen-6-one | Drug Info |
| JNK1 --- JNK3 | 1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)piperidine-3-carboxamide | Drug Info |
| PR --- mRNA of AR | 5-Bromo-2-((1S,5R)-5-hydroxy-2,2,5-trimethyl-6-methylene-cyclohexylmethyl)-4-methoxy-phenol | Drug Info |
| Erbeta --- ER | 7-(4-Hydroxy-phenyl)-naphthalen-2-ol | Drug Info |
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