Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T72545 | ||||
Target Name | Bacterial DNA topoisomerase 4A (Bact parC) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | A-62824 | Drug Info | IC50 = 500 nM | [1] | |
References | |||||
REF 1 | Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent anti... Bioorg Med Chem Lett. 2006 Mar 1;16(5):1272-6. | ||||
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