Target Validation Information
TTD ID T72545
Target Name Bacterial DNA topoisomerase 4A (Bact parC)
Type of Target
Successful
Drug Potency against Target A-62824 Drug Info IC50 = 500 nM [1]
References
REF 1 Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent anti... Bioorg Med Chem Lett. 2006 Mar 1;16(5):1272-6.

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