Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T58238 | ||||
Target Name | Activation B7-1 antigen (CD80) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | Abatacept | Drug Info | Kd = 8.7 nM | [1] | |
References | |||||
REF 1 | Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2). J Immunol. 1996 Feb 1;156(3):1047-54. | ||||
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