Target Validation Information
TTD ID T58238
Target Name Activation B7-1 antigen (CD80)
Type of Target
Successful
Drug Potency against Target Abatacept Drug Info Kd = 8.7 nM [1]
References
REF 1 Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2). J Immunol. 1996 Feb 1;156(3):1047-54.

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