Target Binding Site Detail
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T14928 | Target Info | |||
| Target Name | Protein FAM83B (FA83B) | ||||
| Synonyms | C6orf143 | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | FAM83B | ||||
| UniProt ID | |||||
| Ligand General Information | Top | ||||
|---|---|---|---|---|---|
| Ligand Name | 1,1'-Carbonyldipiperidine | Ligand Info | |||
| Canonical SMILES | C1CCN(CC1)C(=O)N2CCCCC2 | ||||
| InChI | 1S/C11H20N2O/c14-11(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H2 | ||||
| InChIKey | SNOJOKOVTYPHMC-UHFFFAOYSA-N | ||||
| PubChem Compound ID | 21493 | ||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| PDB ID: 5QHK PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000010a | ||||||
| Method | X-ray diffraction | Resolution | 1.61 Å | Mutation | No | [1] |
| PDB Sequence |
GTHIDLLFHP
127 PRAHLLTIKE137 TIRKMIKEAR147 KVIALVMDIF157 TDVDIFKEIV167 EASTRGVSVY 177 ILLDESNFNH187 FLNMTEKQGC197 SVQRLRNIRV207 RTVKGQDYLS217 KTGAKFHGKM 227 EQKFLLVDCQ237 KVMYGSYSYM247 WSFEKAHLSM257 VQIITGQLVE267 SFDEEFRTLY 277 ARSCVPSSF
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| PDB ID: 5QHO PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FMOPL000010a | ||||||
| Method | X-ray diffraction | Resolution | 1.66 Å | Mutation | No | [2] |
| PDB Sequence |
GGTHIDLLFH
12 PPRAHLLTIK22 ETIRKMIKEA32 RKVIALVMDI42 FTDVDIFKEI52 VEASTRGVSV 62 YILLDESNFN72 HFLNMTEKQG82 CSVQRLRNIR92 VRTVKGQDYF109 HGKMEQKFLL 119 VDCQKVMYGS129 YSYMWSFEKA139 HLSMVQIITG149 QLVESFDEEF159 RTLYARSCVP 169 SSFA
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) | ||||
| REF 2 | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) | ||||
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