Target Information

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Target General Information
Different Human System Profiles of Target
References
Different Human System Profiles of Target  Top
Human Similarity Proteins of target is determined by comparing the sequence similarity of all human proteins with the target based on BLAST. The similarity proteins for a target are defined as the proteins with E-value < 0.005 and outside the protein families of the target.
A target that has fewer human similarity proteins outside its family is commonly regarded to possess a greater capacity to avoid undesired interactions and thus increase the possibility of finding successful drugs (Brief Bioinform, 21: 649-662, 2020).
Human Similarity Proteins
Protein Name Pfam ID Percentage of Identity (%) E value
Potassium channel subfamily K member 17 (KCNK17)
PF07885
31.429 (22/70) 9.89E-05
TWIK-related acid-sensitive potassium channel 1 (TASK1)
PF07885
29.661 (35/118) 1.76E-04
Potassium channel subfamily K member 2 (KCNK2)
PF07885
32.967 (30/91) 2.60E-04
Potassium channel subfamily K member 10 (KCNK10)
PF07885
35.938 (23/64) 6.48E-04
Potassium channel subfamily K member 16 (KCNK16)
PF07885
30.769 (20/65) 7.75E-04
Potassium channel subfamily K member 6 (KCNK6)
PF07885
37.037 (20/54) 1.00E-03
Potassium channel subfamily K member 4 (KCNK4)
PF07885
36.170 (17/47) 2.00E-03
Calcium-activated potassium channel KCa4.2 (KCNT2)
PF03493 ; 
PF07885
23.478 (27/115) 3.00E-03
TWIK-related acid-sensitive potassium channel 3 (TASK3)
PF07885
39.130 (18/46) 5.00E-03
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