Target Information
| Target General Information | Top | |||||
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| Target ID |
T79598
(Former ID: TTDI02675)
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| Target Name |
IGFBP2 messenger RNA (IGFBP2 mRNA)
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| Synonyms |
Insulinlike growth factorbinding protein 2 (mRNA); Insulin-like growth factor-binding protein 2 (mRNA); IGFbinding protein 2 (mRNA); IGFBP-2 (mRNA); IGF-binding protein 2 (mRNA); IBP2 (mRNA); IBP-2 (mRNA); BP2 (mRNA)
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| Gene Name |
IGFBP2
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| Target Type |
Literature-reported target
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[1] | ||||
| Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Inhibits IGF-mediated growth and developmental rates.
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| BioChemical Class |
mRNA target
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| UniProt ID | ||||||
| Sequence |
MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAP
PAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELP LQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKP LKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERIST MRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTI RGDPECHLFYNEQQEARGVHTQRMQ Click to Show/Hide
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| Cell-based Target Expression Variations | Top | |||||
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| Cell-based Target Expression Variations | ||||||
| References | Top | |||||
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| REF 1 | Modulation of IGFBP2 mRNA expression in white adipose tissue upon aging and obesity. Horm Metab Res. 2010 Oct;42(11):787-91. | |||||
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