Target Information
Target General Information | Top | |||||
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Target ID |
T78244
(Former ID: TTDR00114)
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Target Name |
Vasoactive intestinal polypeptide receptor (VIPR)
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Synonyms |
VIP-R; VIP receptor
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Gene Name |
NO-GeName
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Target Type |
Discontinued target
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[1] | ||||
Disease | [+] 1 Target-related Diseases | + | ||||
1 | Asthma [ICD-11: CA23] | |||||
BioChemical Class |
GPCR secretin
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UniProt ID |
Drugs and Modes of Action | Top | |||||
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Discontinued Drug(s) | [+] 1 Discontinued Drugs | + | ||||
1 | AR-D-111421 | Drug Info | Discontinued in Phase 2 | Asthma | [2] | |
Mode of Action | [+] 2 Modes of Action | + | ||||
Modulator | [+] 1 Modulator drugs | + | ||||
1 | AR-D-111421 | Drug Info | [1] | |||
Inhibitor | [+] 1 Inhibitor drugs | + | ||||
1 | Ac-HSDAVFTDQYTRLRKQVAAKKYLQSIKQKRYC | Drug Info | [3] |
Target Poor or Non Binders | Top | |||||
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Target Poor or Non Binders |
Target-Related Models and Studies | Top | |||||
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Target Validation |
References | Top | |||||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013264) | |||||
REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013264) | |||||
REF 3 | Engineering of a VPAC2 receptor peptide agonist to impart dipeptidyl peptidase IV stability and enhance in vivo glucose disposal. J Med Chem. 2006 Dec 14;49(25):7545-8. |
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