Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T55352
(Former ID: TTDI00191)
|
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| Target Name |
Amyloid precursor protein (APP)
|
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| Gene Name |
NO-GeName
|
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| Target Type |
Literature-reported target
|
[1] | ||||
| Disease | [+] 1 Target-related Diseases | + | ||||
| 1 | Alzheimer disease [ICD-11: 8A20] | |||||
| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Clinical Trial Drug(s) | [+] 1 Clinical Trial Drugs | + | ||||
| 1 | SHR-1707 | Drug Info | Phase 1 | Alzheimer disease | [2] | |
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | The Intracellular Domain of Amyloid Precursor Protein is a Potential Therapeutic Target in Alzheimer's Disease. Curr Drug Discov Technol. 2014;11(4):243-58. | |||||
| REF 2 | ClinicalTrials.gov (NCT04973189) A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Intravenous Administration of SHR-1707 in Healthy Young Adult and Elderly Subjects. U.S.National Institutes of Health. | |||||
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