Target Information
| Target General Information | Top | |||||
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| Target ID |
T27495
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| Target Name |
Variola virus Envelope phospholipase F13 (VARV p37)
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| Synonyms |
Variola 37 kDa protein; VARV p37K; VARV Palmitoylated EV membrane protein; VARV Envelope protein F13
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| Gene Name |
VARV p37
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| Target Type |
Successful target
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[1] | ||||
| Disease | [+] 1 Target-related Diseases | + | ||||
| 1 | Smallpox [ICD-11: 1E70] | |||||
| Function |
Envelope protein associated with the inner side of the enveloped virion (EV) membrane.
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| UniProt ID | ||||||
| Sequence |
MWPFTSAPAGAKCRLVETLPENMDFRSDHLTTFECFNEIITLAKKYIYIASFCCNPLSTT
RGALIFDKLKEASEKGIKIIVLLDERGKRNLGELQSHCPDINFITVNIDKKNNVGLLLGC FWVSDDERCYVGNASFTGGSIHTIKTLGVYSDYPPLATDLRRRFDTFKAFNSVKNSWLNL YSSACCLPVSTAYHIKNPIGGVFFTDSPEHLLGYSRDLDTDVVIDKLRSAKTSIDIEHLA IVPTTRVDGNSYYWPDIYNSIIEAAINRGVKIRLLVGNWDKNDVYSMATAESLDALCVQN DLSVKVFTIQNNTKLLIVDDEYVHITSANFDGTHYQNHGFVSFNSIDKQLVSEAKKIFER DWVSSHSKSLKI Click to Show/Hide
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| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Approved Drug(s) | [+] 1 Approved Drugs | + | ||||
| 1 | Tecovirimat | Drug Info | Approved | Smallpox | [1] | |
| Mode of Action | [+] 1 Modes of Action | + | ||||
| Inhibitor | [+] 1 Inhibitor drugs | + | ||||
| 1 | Tecovirimat | Drug Info | [1] | |||
| References | Top | |||||
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| REF 1 | Tecovirimat, a p37 envelope protein inhibitor for the treatment of smallpox infection.IDrugs. 2010 Mar;13(3):181-91. Review | |||||
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