Target Information
| Target General Information | Top | |||||
|---|---|---|---|---|---|---|
| Target ID |
T21324
(Former ID: TTDI01577)
|
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| Target Name |
Isomerase unspecific (IsoM)
|
|||||
| Gene Name |
NO-GeName
|
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| Target Type |
Discontinued target
|
[1] | ||||
| Disease | [+] 2 Target-related Diseases | + | ||||
| 1 | Angina pectoris [ICD-11: BA40] | |||||
| 2 | Asthma [ICD-11: CA23] | |||||
| UniProt ID | ||||||
| Drugs and Modes of Action | Top | |||||
|---|---|---|---|---|---|---|
| Discontinued Drug(s) | [+] 2 Discontinued Drugs | + | ||||
| 1 | Isbogrel | Drug Info | Discontinued in Preregistration | Angina pectoris | [2] | |
| 2 | Nafagrel | Drug Info | Discontinued in Phase 2 | Asthma | [3] | |
| Mode of Action | [+] 1 Modes of Action | + | ||||
| Modulator | [+] 2 Modulator drugs | + | ||||
| 1 | Isbogrel | Drug Info | [1] | |||
| 2 | Nafagrel | Drug Info | [4] | |||
| References | Top | |||||
|---|---|---|---|---|---|---|
| REF 1 | Beneficial effect of CV-4151 (Isbogrel), a thromboxane A2 synthase inhibitor, in a rat middle cerebral artery thrombosis model. Thromb Res. 1995 Jul 1;79(1):95-107. | |||||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000413) | |||||
| REF 3 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000433) | |||||
| REF 4 | FMLP actions and its binding sites in isolated human coronary arteries. J Mol Cell Cardiol. 1997 Mar;29(3):881-94. | |||||
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