Target Information
| Target General Information | Top | |||||
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| Target ID |
T17008
(Former ID: TTDI02676)
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| Target Name |
IGFBP5 messenger RNA (IGFBP5 mRNA)
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| Synonyms |
Insulin-like growth factor-binding protein 5 (mRNA); IGFBP-5 (mRNA); IGF-binding protein 5 (mRNA); IBP5 (mRNA); IBP-5 (mRNA)
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| Gene Name |
IGFBP5
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| Target Type |
Literature-reported target
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[1] | ||||
| Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
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| BioChemical Class |
mRNA target
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| UniProt ID | ||||||
| Sequence |
MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA
LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE Click to Show/Hide
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| HIT2.0 ID | T93WPH | |||||
| Cell-based Target Expression Variations | Top | |||||
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| Cell-based Target Expression Variations | ||||||
| References | Top | |||||
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| REF 1 | Correlation between the DNA methylation and gene expression of IGFBP5 in breast cancer. Breast Dis. 2016;36(4):123-131. | |||||
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