Target Information
Target General Information | Top | |||||
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Target ID |
T00564
(Former ID: TTDR01424)
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Target Name |
DUSP9 messenger RNA (DUSP9 mRNA)
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Synonyms |
Mitogen-activated protein kinase phosphatase 4 (mRNA); MKP4 (mRNA); MKP-4 (mRNA); MAP kinase phosphatase 4 (mRNA); Dual specificity protein phosphatase 9 (mRNA)
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Gene Name |
DUSP9
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Target Type |
Literature-reported target
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[1] | ||||
Function |
Has a specificity for the ERK family. Inactivates MAP kinases.
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BioChemical Class |
mRNA target
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UniProt ID | ||||||
EC Number |
EC 3.1.3.16
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Sequence |
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLS
VRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLA YYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADR DSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNL PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTV TVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQA SAASNPPSFFTTPTSDGAFELAPT Click to Show/Hide
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Cell-based Target Expression Variations | Top | |||||
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Cell-based Target Expression Variations |
Target Affiliated Biological Pathways | Top | |||||
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KEGG Pathway | [+] 2 KEGG Pathways | + | ||||
1 | MAPK signaling pathway | |||||
2 | Signaling pathways regulating pluripotency of stem cells | |||||
NetPath Pathway | [+] 2 NetPath Pathways | + | ||||
1 | FSH Signaling Pathway | |||||
2 | IL2 Signaling Pathway | |||||
Reactome | [+] 2 Reactome Pathways | + | ||||
1 | RAF-independent MAPK1/3 activation | |||||
2 | Negative regulation of MAPK pathway |
References | Top | |||||
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REF 1 | US patent application no. 6,566,133, Antisense inhibition of dual specific phosphatase 9 expression. |
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