Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DUVH60
|
|||
| Drug Name |
NM21-1480
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Advanced solid tumour [ICD-11: 2A00-2F9Z; ICD-10: D10-D36, D3A] | Phase 1/2 | [1] | |
| Non-small-cell lung cancer [ICD-11: 2C25] | Phase 1/2 | [1] | ||
| Company |
Numab Therapeutics
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Co-stimulatory molecule 4-1BB (CD137) | Target Info | Modulator | [2] |
| Programmed cell death 1 ligand 1 (PD-L1) | Target Info | Modulator | [2] | |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Cell adhesion molecules (CAMs) | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | Downstream signaling in naï | |||
| Reactome | PD-1 signaling | |||
| WikiPathways | TCR Signaling Pathway | |||
| Costimulation by the CD28 family | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT04442126) A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors. U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of Numab Therapeutics. | |||
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