Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
DP48WE
|
|||
| Drug Name |
Stenoparib
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Ovarian cancer [ICD-11: 2C73; ICD-10: C56; ICD-9: 183] | Phase 2 | [1] | |
| Company |
Allarity Therapeutics
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Poly [ADP-ribose] polymerase 1 (PARP1) | Target Info | Inhibitor | [1] |
| Poly [ADP-ribose] polymerase 2 (PARP2) | Target Info | Inhibitor | [1] | |
| Tankyrase-1 (TNKS-1) | Target Info | Inhibitor | [1] | |
| Tankyrase-2 (TNKS-2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Base excision repair | |||
| NF-kappa B signaling pathway | ||||
| Apoptosis | ||||
| Necroptosis | ||||
| Panther Pathway | FAS signaling pathway | |||
| Pathway Interaction Database | Integrin-linked kinase signaling | |||
| Caspase Cascade in Apoptosis | ||||
| Notch-mediated HES/HEY network | ||||
| Reactome | Dual Incision in GG-NER | |||
| WikiPathways | FAS pathway and Stress induction of HSP regulation | |||
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | ||||
| Nanoparticle triggered regulated necrosis | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Allarity Therapeutics. | |||
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