Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0ZU5F
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| Former ID |
DCL000229
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| Drug Name |
SGX523
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| Synonyms |
SGX-523; SGX523, SGX-523
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 1 | [1], [2] | |
| Therapeutic Class |
Anticancer Agents
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| Company |
SGX Pharma; Eli Lilly
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H13N7S
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| Canonical SMILES |
CN1C=C(C=N1)C2=NN3C(=NN=C3SC4=CC5=C(C=C4)N=CC=C5)C=C2
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| InChI |
1S/C18H13N7S/c1-24-11-13(10-20-24)16-6-7-17-21-22-18(25(17)23-16)26-14-4-5-15-12(9-14)3-2-8-19-15/h2-11H,1H3
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| InChIKey |
BCZUAADEACICHN-UHFFFAOYSA-N
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| CAS Number |
CAS 1022150-57-7
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:90624
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5709). | |||
| REF 2 | ClinicalTrials.gov (NCT00607399) Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors. U.S. National Institutes of Health. | |||
| REF 3 | CenterWatch. Drugs in Clinical Trials Database. CenterWatch. 2008. | |||
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