Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Z8EI
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| Former ID |
DNC004022
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| Drug Name |
6-Allyloxy-9H-purin-2-ylamine
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| Synonyms |
CHEMBL325053; 50663-54-2; O6-Allylguanine; O6-Substituted Guanine Deriv. 15; 6-prop-2-enoxy-7H-purin-2-amine; NU 2028; AC1L45IB; SCHEMBL1263549; BDBM5475; 6-(prop-2-en-1-yloxy)-9H-purin-2-amine; 9H-Purin-2-amine, 6-(2-propen-1-yloxy)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H9N5O
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| Canonical SMILES |
C=CCOC1=NC(=NC2=C1NC=N2)N
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| InChI |
1S/C8H9N5O/c1-2-3-14-7-5-6(11-4-10-5)12-8(9)13-7/h2,4H,1,3H2,(H3,9,10,11,12,13)
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| InChIKey |
HJMGFQNIHIHSCQ-UHFFFAOYSA-N
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| CAS Number |
CAS 50663-54-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | O-6-methylguanine-DNA-alkyltransferase (MGMT) | Target Info | Inhibitor | [1] |
| WikiPathways | DNA Damage Reversal | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Resistance-modifying agents. 8. Inhibition of O(6)-alkylguanine-DNA alkyltransferase by O(6)-alkenyl-, O(6)-cycloalkenyl-, and O(6)-(2-oxoalkyl)gua... J Med Chem. 2000 Nov 2;43(22):4071-83. | |||
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