Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y2TI
|
|||
| Former ID |
DIB012994
|
|||
| Drug Name |
Glionitrin A
|
|||
| Synonyms |
Glionitrin A; CHEMBL550491
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Company |
Korea Institute of Science and Technology
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H11N3O5S2
|
|||
| Canonical SMILES |
CN1C(=O)C23CC4=C(N2C(=O)C1(SS3)CO)C=C(C=C4)[N+](=O)[O-]
|
|||
| InChI |
1S/C13H11N3O5S2/c1-14-10(18)12-5-7-2-3-8(16(20)21)4-9(7)15(12)11(19)13(14,6-17)23-22-12/h2-4,17H,5-6H2,1H3/t12-,13-/m0/s1
|
|||
| InChIKey |
VRFJINVAZRAFHH-STQMWFEESA-N
|
|||
| CAS Number |
CAS 1116153-15-1
|
|||
| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:65967
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Glionitrin A, a new diketopiperazine disulfide, activates ATM-ATR-Chk1/2 via 53BP1 phosphorylation in DU145 cells and shows antitumor effect in xenograft model. Biol Pharm Bull. 2014;37(3):378-86. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.