Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QK5X
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| Former ID |
DNAP001680
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| Drug Name |
Enzalutamide
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| Synonyms |
MDV3100; Enzalutamide (AR inhibitor)
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| Drug Type |
Small molecular drug
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| Indication | Prostate cancer [ICD-11: 2C82.0; ICD-10: C61; ICD-9: 185] | Approved | [1] | |
| Company |
Astellas Pharma
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H16F4N4O2S
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| Canonical SMILES |
CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C
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| InChI |
1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
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| InChIKey |
WXCXUHSOUPDCQV-UHFFFAOYSA-N
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| CAS Number |
CAS 915087-33-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
22422973, 26557832, 33334455, 85286065, 99437051, 103756429, 124757115, 125163919, 125299336, 125749051, 126731384, 131480739, 135261179, 135684120, 135727393, 136367372, 136367882, 136375508, 137009352, 137275964, 143499468, 144116190, 151990441, 152237529, 152258872, 152344309, 160645896, 160647721, 160821662, 162011754, 162036208, 162196987, 163091639, 163312249, 164041953, 164154607, 164193917, 164761729, 165245624, 172093747, 172914062, 174477518, 174531457, 175267791, 175427141, 177748753, 178103418, 185989448, 188899565, 198993053
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| ChEBI ID |
CHEBI:68534
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| ADReCS Drug ID | BADD_D00775 | |||
| SuperDrug ATC ID |
L02BB03
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| Drug Resistance Mutation (DRM) | Top | |||
|---|---|---|---|---|
| DRM | DRM Info | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Nat Rev Drug Discov. 2013 Feb;12(2):87-90. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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