Drug Information
Drug General Information | Top | |||
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Drug ID |
D0P2MH
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Former ID |
DIB016275
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Drug Name |
BTS-67582
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Synonyms |
1,1-Dimethyl-2-(2-morpholinophenyl)guanidine fumarate
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Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Discontinued in Phase 2 | [1] | |
Structure |
Download2D MOL
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Formula |
C17H24N4O5
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Canonical SMILES |
CN(C)C(=NC1=CC=CC=C1N2CCOCC2)N.C(=CC(=O)O)C(=O)O
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InChI |
1S/C13H20N4O.C4H4O4/c1-16(2)13(14)15-11-5-3-4-6-12(11)17-7-9-18-10-8-17;5-3(6)1-2-4(7)8/h3-6H,7-10H2,1-2H3,(H2,14,15);1-2H,(H,5,6)(H,7,8)/b;2-1+
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InChIKey |
FFEKJBVVAJTQST-WLHGVMLRSA-N
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CAS Number |
CAS 161748-40-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | ATP-binding cassette transporter C9 (ABCC9) | Target Info | Modulator | [2], [3], [4] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001595) | |||
REF 2 | BTS-67582 (Knoll Pharmaceuticals Co). IDrugs. 1999 Apr;2(4):355-9. | |||
REF 3 | The effect of an insulin releasing agent, BTS 67582, on advanced glycation end product formation in vitro. Life Sci. 1999;64(16):1427-34. | |||
REF 4 | Evaluation of BTS 67 582, a novel antidiabetic agent, in normal and diabetic rats. Br J Pharmacol. 1997 Mar;120(6):1135-43. |
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