Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0OP3D
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| Former ID |
DIB018929
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| Drug Name |
AZ960
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| Synonyms |
AZ 960; AZ-960
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C18H16F2N6
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| Canonical SMILES |
CC1=CC(=NN1)NC2=C(C=C(C(=N2)NC(C)C3=CC=C(C=C3)F)C#N)F
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| InChI |
1S/C18H16F2N6/c1-10-7-16(26-25-10)23-18-15(20)8-13(9-21)17(24-18)22-11(2)12-3-5-14(19)6-4-12/h3-8,11H,1-2H3,(H3,22,23,24,25,26)/t11-/m0/s1
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| InChIKey |
SUNXHXDJOIXABJ-NSHDSACASA-N
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| CAS Number |
CAS 905586-69-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
56418853, 80989931, 124360687, 124757652, 125164456, 131282705, 131346661, 135727832, 136340354, 136367468, 136368078, 136920277, 144115652, 162011558, 162037822, 162202683, 163642861, 163908032, 164194016, 172918163, 174006722, 180386991, 198964561, 223705121, 224184199, 239809598, 244548302, 252160442, 252166685, 252543285
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2. J Biol Chem. 2008 Nov 21;283(47):32334-43. | |||
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