Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0N7VL
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| Former ID |
DNC011291
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| Drug Name |
Asp-BrPmp-Leu
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| Synonyms |
Asp-BrPmp-Leu; CHEMBL1289231; BDBM50331945
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H29BrN3O9P
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| Canonical SMILES |
CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=C(C=C1)C(P(=O)(O)O)Br)NC(=O)C(CC(=O)O)N
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| InChI |
1S/C20H29BrN3O9P/c1-10(2)7-15(20(29)30)24-19(28)14(23-18(27)13(22)9-16(25)26)8-11-3-5-12(6-4-11)17(21)34(31,32)33/h3-6,10,13-15,17H,7-9,22H2,1-2H3,(H,23,27)(H,24,28)(H,25,26)(H,29,30)(H2,31,32,33)/t13-,14-,15-,17?/m0/s1
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| InChIKey |
VZSILTSENHCLNI-CKSGOKGCSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukocyte common antigen (PTPRC) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cell adhesion molecules (CAMs) | |||
| T cell receptor signaling pathway | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Primary immunodeficiency | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Panther Pathway | B cell activation | |||
| JAK/STAT signaling pathway | ||||
| T cell activation | ||||
| Pathway Interaction Database | BCR signaling pathway | |||
| TCR signaling in naï | ||||
| TCR signaling in naï | ||||
| CXCR4-mediated signaling events | ||||
| Reactome | Phosphorylation of CD3 and TCR zeta chains | |||
| Other semaphorin interactions | ||||
| WikiPathways | Interferon type I signaling pathways | |||
| EPO Receptor Signaling | ||||
| B Cell Receptor Signaling Pathway | ||||
| TCR signaling | ||||
| Semaphorin interactions | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors. Bioorg Med Chem. 2010 Dec 15;18(24):8679-86. | |||
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