Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0JY8T
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| Former ID |
DIB010764
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| Drug Name |
Bazedoxifene
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| Synonyms |
Brilence; Conbriza; Viviant; Bazedoxifene acetate; TSE-424; WAY-140424; WAY-TES 424
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| Drug Type |
Small molecular drug
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| Indication | Osteopetrosis [ICD-11: LD24.10; ICD-10: Q78.2] | Approved | [1], [2], [3] | |
| Company |
Ligand Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C30H34N2O3
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| Canonical SMILES |
CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCCC4)C5=CC=C(C=C5)O
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| InChI |
1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3
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| InChIKey |
UCJGJABZCDBEDK-UHFFFAOYSA-N
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| CAS Number |
CAS 198481-32-2
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:135947
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| ADReCS Drug ID | BADD_D00215 | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7355). | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | ClinicalTrials.gov (NCT02090400) Switching From Oral Bisphosphonates to Bazedoxifene to Evaluate Effects on Bone Mineral Density in Postmenopausal Women. U.S. National Institutes of Health. | |||
| REF 4 | Bazedoxifene, a selective estrogen receptor modulator: effects on the endometrium, ovaries, and breast from a randomized controlled trial in osteoporotic postmenopausal women. Menopause. 2009 Nov-Dec;16(6):1109-15. | |||
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