Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0I5QX
|
|||
| Former ID |
DIB003697
|
|||
| Drug Name |
Etanercept
|
|||
| Synonyms |
Etanercept (sciatica); Etanercept (sciatica), BioAssets Development; Etanercept (sciatica), Cephalon
Click to Show/Hide
|
|||
| Drug Type |
Monoclonal antibody
|
|||
| Indication | Arthritis [ICD-11: FA20; ICD-9: 714] | Approved | [1] | |
| Sciatica [ICD-11: ME84.3; ICD-10: M54.3] | Phase 3 | [2], [3] | ||
| Pemphigus vulgaris [ICD-11: EB40] | Phase 2 | [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21] | ||
| Company |
AstraZeneca
|
|||
| ADReCS Drug ID | BADD_D00838 | |||
| Interaction between the Drug and Microbe | Top | |||
|---|---|---|---|---|
| The Abundace of Studied Microbe(s) Regulated by Drug | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Gut microbiota | ||||
|
Studied Microbe: Burkholderiales
Show/Hide Hierarchy
|
[22] | |||
| Hierarchy | ||||
| Abundance Change | Increase | |||
| Experimental Species | Human | Experimental Sample | Faeces | |
| Disease or Condition | Rheumatoid arthritis | |||
| Description | The abundance of Burkholderiales was increased by Etanercept. | |||
|
Studied Microbe: Nostocales
Show/Hide Hierarchy
|
[22] | |||
| Hierarchy | ||||
| Abundance Change | Increase | |||
| Experimental Species | Human | Experimental Sample | Faeces | |
| Disease or Condition | Rheumatoid arthritis | |||
| Description | The abundance of Nostocales was increased by Etanercept. | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6789). | |||
| REF 3 | Etanercept, a TNF antagonist for treatment for psoriatic arthritis and psoriasis. Skin Therapy Lett. 2003 Jan;8(1):1-4. | |||
| REF 4 | ClinicalTrials.gov (NCT00135720) Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaris | |||
| REF 5 | ClinicalTrials.gov (NCT00001901) Etanercept to Treat Wegener's Granulomatosis | |||
| REF 6 | ClinicalTrials.gov (NCT00001954) Etanercept Therapy for Sjogren's Syndrome | |||
| REF 7 | ClinicalTrials.gov (NCT01289743) Etanercept (Enbrel) in Ankylosing Spondylitis | |||
| REF 8 | ClinicalTrials.gov (NCT01289730) Etanercept (Enbrel) in Undifferentiated Spondyloarthritis | |||
| REF 9 | ClinicalTrials.gov (NCT02656082) Targeted Therapy Using Intradermal Injection of Etanercept for Remission Induction in Discoid Lupus Erythematosus | |||
| REF 10 | ClinicalTrials.gov (NCT00034060) The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women With Rheumatoid Arthritis and the Effect of Treatment With Etanercept | |||
| REF 11 | ClinicalTrials.gov (NCT00107991) Etanercept for Treatment of Hidradenitis | |||
| REF 12 | ClinicalTrials.gov (NCT00141791) Study Evaluating Etanercept in Moderate to Severe Asthma | |||
| REF 13 | ClinicalTrials.gov (NCT00141739) Study of Etanercept for the Prevention of Complications Resulting From Hematopoietic Stem Cell Transplantation (HSCT) | |||
| REF 14 | ClinicalTrials.gov (NCT00509600) Etanercept (Enbrel) for Juvenile Myelomonocytic Leukemia | |||
| REF 15 | ClinicalTrials.gov (NCT00141726) Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant | |||
| REF 16 | ClinicalTrials.gov (NCT00141713) The Use of Etanercept (Enbrel) in the Treatment of Acute Graft-Versus-Host Disease | |||
| REF 17 | ClinicalTrials.gov (NCT01730495) Tumor Necrosis Factor-alpha Inhibition Using Etanercept in Chronic Fatigue Syndrome | |||
| REF 18 | ClinicalTrials.gov (NCT00134368) Study of the Efficacy and Safety of Etanercept in Adults With Vitiligo | |||
| REF 19 | ClinicalTrials.gov (NCT00063869) Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis | |||
| REF 20 | ClinicalTrials.gov (NCT00005007) Etanercept for Wegener's Granulomatosis | |||
| REF 21 | ClinicalTrials.gov (NCT00006070) Etanercept (Enbrel) to Treat Pain and Swelling After Third Molar Extraction | |||
| REF 22 | Emerging Insights on the Interaction Between Anticancer and Immunosuppressant Drugs and Intestinal Microbiota in Pediatric Patients. Clin Transl Sci. 2020 Mar;13(2):238-259. | |||
| REF 23 | The potential of biologics for the treatment of asthma. Nat Rev Drug Discov. 2012 Dec;11(12):958-72. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.