| Target and Pathway |
Top |
| Target(s) |
Extracellular signal-regulated kinase 1 (ERK1) |
Target Info
|
Inhibitor |
[1] |
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KEGG Pathway
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MAPK signaling pathway
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ErbB signaling pathway
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Ras signaling pathway
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Rap1 signaling pathway
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cGMP-PKG signaling pathway
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cAMP signaling pathway
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Chemokine signaling pathway
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HIF-1 signaling pathway
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FoxO signaling pathway
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Sphingolipid signaling pathway
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Oocyte meiosis
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mTOR signaling pathway
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PI3K-Akt signaling pathway
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Adrenergic signaling in cardiomyocytes
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Vascular smooth muscle contraction
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Dorso-ventral axis formation
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TGF-beta signaling pathway
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Axon guidance
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VEGF signaling pathway
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Osteoclast differentiation
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Focal adhesion
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Adherens junction
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Gap junction
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Signaling pathways regulating pluripotency of stem cells
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Platelet activation
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Toll-like receptor signaling pathway
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NOD-like receptor signaling pathway
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Natural killer cell mediated cytotoxicity
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T cell receptor signaling pathway
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B cell receptor signaling pathway
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Fc epsilon RI signaling pathway
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Fc gamma R-mediated phagocytosis
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TNF signaling pathway
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Circadian entrainment
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Long-term potentiation
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Neurotrophin signaling pathway
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Retrograde endocannabinoid signaling
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Glutamatergic synapse
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Cholinergic synapse
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Serotonergic synapse
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Long-term depression
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Regulation of actin cytoskeleton
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Insulin signaling pathway
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GnRH signaling pathway
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Progesterone-mediated oocyte maturation
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Estrogen signaling pathway
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Melanogenesis
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Prolactin signaling pathway
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Thyroid hormone signaling pathway
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Oxytocin signaling pathway
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Type II diabetes mellitus
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Aldosterone-regulated sodium reabsorption
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Alzheimer's disease
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Prion diseases
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Alcoholism
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Shigellosis
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Salmonella infection
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Pertussis
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Leishmaniasis
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Tuberculosis
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Hepatitis C
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Hepatitis B
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Influenza A
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Pathways in cancer
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Viral carcinogenesis
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Proteoglycans in cancer
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Colorectal cancer
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Renal cell carcinoma
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Pancreatic cancer
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Endometrial cancer
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Glioma
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Prostate cancer
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Thyroid cancer
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Melanoma
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Bladder cancer
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Chronic myeloid leukemia
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Acute myeloid leukemia
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Non-small cell lung cancer
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Central carbon metabolism in cancer
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Choline metabolism in cancer
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NetPath Pathway
|
IL5 Signaling Pathway
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TCR Signaling Pathway
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Panther Pathway
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Alzheimer disease-amyloid secretase pathway
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Angiogenesis
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Apoptosis signaling pathway
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B cell activation
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EGF receptor signaling pathway
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Endothelin signaling pathway
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FGF signaling pathway
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Inflammation mediated by chemokine and cytokine signaling pathway
|
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Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade
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Integrin signalling pathway
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Interferon-gamma signaling pathway
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Interleukin signaling pathway
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PDGF signaling pathway
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Parkinson disease
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TGF-beta signaling pathway
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T cell activation
|
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Toll receptor signaling pathway
|
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VEGF signaling pathway
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Ras Pathway
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Angiotensin II-stimulated signaling through G proteins and beta-arrestin
|
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CCKR signaling map ST
|
|
Pathway Interaction Database
|
Fc-epsilon receptor I signaling in mast cells
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Endothelins
|
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BCR signaling pathway
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Signaling events mediated by PRL
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ErbB4 signaling events
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GMCSF-mediated signaling events
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Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
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S1P3 pathway
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EPHB forward signaling
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Osteopontin-mediated events
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S1P4 pathway
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Presenilin action in Notch and Wnt signaling
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TRAIL signaling pathway
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CDC42 signaling events
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Signaling events regulated by Ret tyrosine kinase
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Angiopoietin receptor Tie2-mediated signaling
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S1P1 pathway
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Regulation of Telomerase
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Netrin-mediated signaling events
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
|
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Glucocorticoid receptor regulatory network
|
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Arf6 downstream pathway
|
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mTOR signaling pathway
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IL2-mediated signaling events
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EGF receptor (ErbB1) signaling pathway
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Ras signaling in the CD4+ TCR pathway
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Ceramide signaling pathway
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Integrins in angiogenesis
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IFN-gamma pathway
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ErbB1 downstream signaling
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ATF-2 transcription factor network
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ErbB2/ErbB3 signaling events
|
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ALK1 signaling events
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PDGFR-beta signaling pathway
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Neurotrophic factor-mediated Trk receptor signaling
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Syndecan-1-mediated signaling events
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Retinoic acid receptors-mediated signaling
|
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Nongenotropic Androgen signaling
|
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CXCR3-mediated signaling events
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VEGFR1 specific signals
|
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Regulation of cytoplasmic and nuclear SMAD2/3 signaling
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Signaling events mediated by Stem cell factor receptor (c-Kit)
|
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Signaling events mediated by VEGFR1 and VEGFR2
|
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Syndecan-2-mediated signaling events
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Cellular roles of Anthrax toxin
|
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S1P2 pathway
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Trk receptor signaling mediated by the MAPK pathway
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Downstream signaling in naï
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VEGFR3 signaling in lymphatic endothelium
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Alpha-synuclein signaling
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FGF signaling pathway
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Reactome
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MAPK3 (ERK1) activation
|
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RAF-independent MAPK1/3 activation
|
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ISG15 antiviral mechanism
|
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ERK/MAPK targets
|
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Regulation of actin dynamics for phagocytic cup formation
|
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Oxidative Stress Induced Senescence
|
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Senescence-Associated Secretory Phenotype (SASP)
|
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Oncogene Induced Senescence
|
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FCERI mediated MAPK activation
|
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Regulation of HSF1-mediated heat shock response
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NCAM signaling for neurite out-growth
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Activation of the AP-1 family of transcription factors
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Thrombin signalling through proteinase activated receptors (PARs)
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Negative regulation of FGFR1 signaling
|
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Negative regulation of FGFR2 signaling
|
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Negative regulation of FGFR3 signaling
|
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Negative regulation of FGFR4 signaling
|
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RHO GTPases Activate WASPs and WAVEs
|
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RAF/MAP kinase cascade
|
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MAP2K and MAPK activation
|
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Negative feedback regulation of MAPK pathway
|
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Negative regulation of MAPK pathway
|
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Signal attenuation
|
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Advanced glycosylation endproduct receptor signaling
|
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Gastrin-CREB signalling pathway via PKC and MAPK
|
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Growth hormone receptor signaling
|
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WikiPathways
|
Toll-like receptor signaling pathway
|
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Serotonin Receptor 4/6/7 and NR3C Signaling
|
|
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
|
|
Serotonin HTR1 Group and FOS Pathway
|
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TCR Signaling Pathway
|
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Hypothetical Network for Drug Addiction
|
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EPO Receptor Signaling
|
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TGF Beta Signaling Pathway
|
|
Regulation of Actin Cytoskeleton
|
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IL-2 Signaling Pathway
|
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Insulin Signaling
|
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MAPK Cascade
|
|
IL-4 Signaling Pathway
|
|
MAPK Signaling Pathway
|
|
IL-6 signaling pathway
|
|
Signaling of Hepatocyte Growth Factor Receptor
|
|
Kit receptor signaling pathway
|
|
TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
|
|
IL-3 Signaling Pathway
|
|
Cardiac Hypertrophic Response
|
|
MAP kinase activation in TLR cascade
|
|
Fc epsilon receptor (FCERI) signaling
|
|
RAF/MAP kinase cascade
|
|
Structural Pathway of Interleukin 1 (IL-1)
|
|
Genes and (Common) Pathways Underlying Drug Addiction
|
|
Signal Transduction of S1P Receptor
|
|
PDGF Pathway
|
|
Alpha 6 Beta 4 signaling pathway
|
|
Spinal Cord Injury
|
|
BDNF signaling pathway
|
|
Integrated Pancreatic Cancer Pathway
|
|
Oncostatin M Signaling Pathway
|
|
Corticotropin-releasing hormone
|
|
Interleukin-11 Signaling Pathway
|
|
AGE/RAGE pathway
|
|
TNF alpha Signaling Pathway
|
|
Prostate Cancer
|
|
Signaling Pathways in Glioblastoma
|
|
TSLP Signaling Pathway
|
|
IL-9 Signaling Pathway
|
|
IL17 signaling pathway
|
|
Alzheimers Disease
|
|
IL-7 Signaling Pathway
|
|
TWEAK Signaling Pathway
|
|
FSH signaling pathway
|
|
Leptin signaling pathway
|
|
RANKL/RANK Signaling Pathway
|
|
IL-1 signaling pathway
|
|
Thrombin signalling through proteinase activated receptors (PARs)
|
|
Signaling by Insulin receptor
|
|
Signaling by FGFR
|
|
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
|
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L1CAM interactions
|
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Advanced glycosylation endproduct receptor signaling
|
|
Apoptosis Modulation and Signaling
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
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Regulation of toll-like receptor signaling pathway
|
|
Osteopontin Signaling
|
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IL-5 Signaling Pathway
|
