Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C8WA
|
|||
| Former ID |
DNC002200
|
|||
| Drug Name |
ISIS 133242
|
|||
| Drug Type |
Antisense drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DUSP5 messenger RNA (DUSP5 mRNA) | Target Info | . | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| NetPath Pathway | IL5 Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| TCR Signaling Pathway | ||||
| Pathway Interaction Database | Direct p53 effectors | |||
| ATF-2 transcription factor network | ||||
| Reactome | RAF-independent MAPK1/3 activation | |||
| Negative regulation of MAPK pathway | ||||
| WikiPathways | MAPK Signaling Pathway | |||
| Endoderm Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 6,867,039, Antisense modulation of dual specific phosphatase 5 expression. | |||
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