Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0BJ7W
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| Former ID |
DIB004292
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| Drug Name |
GLPG-0492
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| Synonyms |
G-100192; Selective androgen receptor modulators, Galapagos; Selective androgen receptor modulators, ProSkelia; Selective androgen receptor modulators, ProStrakan; SARMs (osteoporosis), ProSkelia; SARMs (osteoporosis), ProStraken; SARMs (osteoporosis/cachexia), Galapagos
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| Indication | Cachexia [ICD-11: MG20; ICD-10: R64; ICD-9: 799.4] | Preclinical | [1] | |
| Company |
ProSkelia Pharmaceuticals SAS
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| Structure |
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Download2D MOL |
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| Formula |
C19H14F3N3O3
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| Canonical SMILES |
CN1C(=O)N(C(=O)C1(CO)C2=CC=CC=C2)C3=CC(=C(C=C3)C#N)C(F)(F)F
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| InChI |
1S/C19H14F3N3O3/c1-24-17(28)25(14-8-7-12(10-23)15(9-14)19(20,21)22)16(27)18(24,11-26)13-5-3-2-4-6-13/h2-9,26H,11H2,1H3/t18-/m1/s1
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| InChIKey |
VAJGULUVTFDTAS-GOSISDBHSA-N
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| CAS Number |
CAS 1215085-92-9
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018432) | |||
| REF 2 | GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res. 2013 Jun;72:9-24. | |||
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