Drug General Information
Drug ID
D0B5PV
Drug Name
CART-EGFRvIII T cells
Drug Type
CAR T Cell Therapy
Indication Recurrent glioblastoma [ICD-11: 2A00.00; ICD-10: C71] Phase 1 [1]
Glioma [ICD-11: 2A00.0; ICD-9: 191] Clinical trial [2]
Company
University of Pennsylvania
Target and Pathway
Target(s) Epidermal growth factor receptor variant III (EGFR vIII) Target Info CAR-T-Cell-Therapy [1], [2]
References
REF 1 ClinicalTrials.gov (NCT03726515) CART-EGFRvIII + Pembrolizumab in GBM
REF 2 ClinicalTrials.gov (NCT02209376) Autologous T Cells Redirected to EGFRVIII-With a Chimeric Antigen Receptor in Patients With EGFRVIII+ Glioblastoma

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