| Target and Pathway |
Top |
| Target(s) |
Inhibitor of nuclear factor kappa-B kinase beta (IKKB) |
Target Info
|
Inhibitor |
[2] |
|
KEGG Pathway
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MAPK signaling pathway
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Ras signaling pathway
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Chemokine signaling pathway
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NF-kappa B signaling pathway
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FoxO signaling pathway
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mTOR signaling pathway
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PI3K-Akt signaling pathway
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Apoptosis
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Osteoclast differentiation
|
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Toll-like receptor signaling pathway
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NOD-like receptor signaling pathway
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RIG-I-like receptor signaling pathway
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Cytosolic DNA-sensing pathway
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T cell receptor signaling pathway
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B cell receptor signaling pathway
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TNF signaling pathway
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Neurotrophin signaling pathway
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Insulin signaling pathway
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Adipocytokine signaling pathway
|
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Type II diabetes mellitus
|
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Non-alcoholic fatty liver disease (NAFLD)
|
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Epithelial cell signaling in Helicobacter pylori infection
|
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Shigellosis
|
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Hepatitis C
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Hepatitis B
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Influenza A
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HTLV-I infection
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Herpes simplex infection
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Epstein-Barr virus infection
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Pathways in cancer
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MicroRNAs in cancer
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Pancreatic cancer
|
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Prostate cancer
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Chronic myeloid leukemia
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Acute myeloid leukemia
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Small cell lung cancer
|
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Panther Pathway
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Apoptosis signaling pathway
|
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B cell activation
|
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Inflammation mediated by chemokine and cytokine signaling pathway
|
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Interleukin signaling pathway
|
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PDGF signaling pathway
|
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T cell activation
|
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Toll receptor signaling pathway
|
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Pathwhiz Pathway
|
Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
|
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Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
|
|
Pathway Interaction Database
|
Fc-epsilon receptor I signaling in mast cells
|
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BCR signaling pathway
|
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GMCSF-mediated signaling events
|
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Atypical NF-kappaB pathway
|
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TCR signaling in naï
|
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Canonical NF-kappaB pathway
|
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TRAIL signaling pathway
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TCR signaling in naï
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FAS (CD95) signaling pathway
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IL1-mediated signaling events
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mTOR signaling pathway
|
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TNF receptor signaling pathway
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FoxO family signaling
|
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p75(NTR)-mediated signaling
|
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Validated transcriptional targets of TAp63 isoforms
|
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Endogenous TLR signaling
|
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Reactome
|
Activation of NF-kappaB in B cells
|
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NOD1/2 Signaling Pathway
|
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RIP-mediated NFkB activation via ZBP1
|
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p75NTR recruits signalling complexes
|
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NF-kB is activated and signals survival
|
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FCERI mediated NF-kB activation
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TAK1 activates NFkB by phosphorylation and activation of IKKs complex
|
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Interleukin-1 signaling
|
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Regulation of TNFR1 signaling
|
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TNFR1-induced NFkappaB signaling pathway
|
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IKBKB deficiency causes SCID
|
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IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
|
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IkBA variant leads to EDA-ID
|
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CLEC7A (Dectin-1) signaling
|
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MAP3K8 (TPL2)-dependent MAPK1/3 activation
|
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TRAF6 mediated NF-kB activation
|
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NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
|
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IRAK1 recruits IKK complex
|
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IKK complex recruitment mediated by RIP1
|
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IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
|
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WikiPathways
|
Toll-like receptor signaling pathway
|
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Estrogen signaling pathway
|
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TCR Signaling Pathway
|
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Insulin Signaling
|
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IL-4 Signaling Pathway
|
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MAPK Signaling Pathway
|
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NLR Proteins
|
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Hair Follicle Development: Induction (Part 1 of 3)
|
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MyD88 cascade initiated on plasma membrane
|
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Cardiac Hypertrophic Response
|
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Cytosolic sensors of pathogen-associated DNA
|
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MyD88 dependent cascade initiated on endosome
|
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Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
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MyD88:Mal cascade initiated on plasma membrane
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Fc epsilon receptor (FCERI) signaling
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MyD88-independent cascade
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Signaling by the B Cell Receptor (BCR)
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TAK1 activates NFkB by phosphorylation and activation of IKKs complex
|
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Structural Pathway of Interleukin 1 (IL-1)
|
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EBV LMP1 signaling
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Polycystic Kidney Disease Pathway
|
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Apoptosis
|
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Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
|
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BDNF signaling pathway
|
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Interleukin-11 Signaling Pathway
|
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AGE/RAGE pathway
|
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TNF alpha Signaling Pathway
|
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B Cell Receptor Signaling Pathway
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IL17 signaling pathway
|
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TWEAK Signaling Pathway
|
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Leptin signaling pathway
|
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RANKL/RANK Signaling Pathway
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Signalling by NGF
|
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IL-1 signaling pathway
|
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TCR signaling
|
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RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
|
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Interleukin-1 signaling
|
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Apoptosis Modulation and Signaling
|
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Type II diabetes mellitus
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
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Regulation of toll-like receptor signaling pathway
|
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Osteopontin Signaling
|
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NOD pathway
|
