Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A7XQ
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| Former ID |
DIB010940
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| Drug Name |
ON-044580
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| Synonyms |
ON-04 series (cancer), Onconova; JAK2/Bcr-Abl kinase inhibitors (cancer), Onconova
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Company |
Onconova Therapeutics Inc
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| Structure |
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Download2D MOL |
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| Formula |
C16H13BrO3S
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| Canonical SMILES |
C1=CC(=CC=C1CSCC(=O)C2=CC=C(C=C2)C(=O)O)Br
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| InChI |
1S/C16H13BrO3S/c17-14-7-1-11(2-8-14)9-21-10-15(18)12-3-5-13(6-4-12)16(19)20/h1-8H,9-10H2,(H,19,20)
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| InChIKey |
KTQGMLFAHVKKNV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A Non-ATP-Competitive Dual Inhibitor of JAK2 and BCR-ABL Kinases: Elucidation of a Novel Therapeutic Spectrum Based on Substrate Competitive Inhibition. Genes Cancer. 2010 Apr;1(4):331-45. | |||
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