Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09QEI
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| Former ID |
DAP000048
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| Drug Name |
Pentoxifylline
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| Synonyms |
Agapurin; Azupentat; Dimethyloxohexylxanthine; Durapental; Hemovas; Ikomio; Oxpentifylline; PENTOXYPHYLINE;PNX; Pentoxifilina; Pentoxifyllin; Pentoxifyllinum; Pentoxil; Pentoxiphyllin; Pentoxiphylline; Pentoxiphyllium; Pentoxyfylline; Pentoxyphyllin; Pentoxyphylline; Ralofect; Rentylin; Torental; Trental;Vasofirin; Vazofirin; Agapurin Retard; BL 191; BL191; EHT 0201; EHT0201; IN1161; P 1784; Artal (TN); BL-191; EHT-0201; EHT-201; Flexital (TN); Pentox (TN); Pentoxifilina [INN-Spanish]; Pentoxifyllinum [INN-Latin]; Pentoxil (TN); Pentoxin (TN); Trental (TN); Cis-9-Octadecenoyl coenzyme A; Pentoxifylline [USAN:INN:JAN]; Pentoxifylline (JAN/USP/INN); 1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion; 1-(5-Oxohexyl)-3,7-dimethylxanthine; 1-(5-Oxohexyl)theobromine; 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione; 3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione; 3,7-Dimethyl-1-(5-oxohexyl) xantine; 3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione; 3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione; 3,7-Dimethyl-1-(5-oxohexyl)xanthine; 3,7-Dimethyl-1-(5-oxohexyl)xantine; 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
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| Drug Type |
Small molecular drug
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| Indication | Intermittent claudication [ICD-11: BD40.00; ICD-9: 440.21] | Approved | [1], [2] | |
| Therapeutic Class |
Vasodilator Agents
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| Company |
Aventis Pharmaceuticals Inc.
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H18N4O3
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| Canonical SMILES |
CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
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| InChI |
1S/C13H18N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8H,4-7H2,1-3H3
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| InChIKey |
BYPFEZZEUUWMEJ-UHFFFAOYSA-N
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| CAS Number |
CAS 6493-05-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9628, 498489, 597360, 857899, 1916632, 3153146, 7703125, 7847567, 7889976, 8026211, 8150006, 8152909, 10321577, 10531727, 10589689, 11111613, 11111614, 11335904, 11361143, 11364338, 11366900, 11369462, 11373038, 11374032, 11377624, 11462115, 11466224, 11467344, 11484957, 11485808, 11488997, 11491635, 11492042, 11495258, 14799544, 17405494, 25623640, 26538474, 26612497, 26679957, 26719692, 26747196, 26747197, 26759331, 29223826, 46386861, 46393770, 46505940, 46511426, 47216797
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| ChEBI ID |
CHEBI:7986
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| ADReCS Drug ID | BADD_D01731 | |||
| SuperDrug ATC ID |
C04AD03
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| SuperDrug CAS ID |
cas=006493056
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7095). | |||
| REF 2 | New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202. | |||
| REF 3 | Targeted therapies in myelodysplastic syndromes: ASH 2003 review. Semin Hematol. 2004 Apr;41(2 Suppl 4):13-20. | |||
| REF 4 | Tumor necrosis factor alpha in the pathogenesis of cerebral malaria. Cell Mol Life Sci. 2003 Aug;60(8):1623-35. | |||
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