Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09NNA
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| Former ID |
DAP000840
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| Drug Name |
Dromostanolone
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| Synonyms |
Drostanolo; Drostanolon; Drostanolona; Drostanolone; Drostanolonum; Medrosteron; Medrotestron; Methalone; Metholone; Prometholone; Drostanolo [DCIT]; SKI 27719; Drolban (TN); Drostanolona [INN-Spanish]; Drostanolone [INN:BAN]; Drostanolonum [INN-Latin]; Dihydro-2alpha-methyltestosterone; Dihydro-2-alpha-methyltestosterone; Dihydro-2.alpha.-methyltestosterone; Androstan-3-one, 17-hydroxy-2-methyl-, (2alpha,5alpha,17beta)-(9CI); (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one; (2alpha,5alpha,17beta)-17-hydroxy-2-methylandrostan-3-one; 17 beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one; 17-beta-Hydroxy-2-alpha-methyl-5-alpha-androstan-3-one; 17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one; 2-alpha-Methyl-17-beta-hydroxy-5-alpha-androstan-3-one; 2-alpha-Methyldihydrotestosterone; 2.alpha.-Methyldihydrotestosterone; 2a-methylandrostan-17b-ol-3-one; 2alpha-Methyldihydrotestosterone
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| Drug Type |
Small molecular drug
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| Indication | Mammary tumour [ICD-11: 2C60-2C6Z] | Approved | [1], [2] | |
| Therapeutic Class |
Anabolic Agents
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| Company |
Eli Lilly And Co
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H32O2
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| Canonical SMILES |
CC1CC2(C(CCC3C2CCC4(C3CCC4O)C)CC1=O)C
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| InChI |
1S/C20H32O2/c1-12-11-20(3)13(10-17(12)21)4-5-14-15-6-7-18(22)19(15,2)9-8-16(14)20/h12-16,18,22H,4-11H2,1-3H3/t12-,13+,14+,15+,16+,18+,19+,20+/m1/s1
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| InChIKey |
IKXILDNPCZPPRV-RFMGOVQKSA-N
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| CAS Number |
CAS 58-19-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
76938, 7848597, 9378212, 30427136, 48415931, 56394853, 57400031, 71840221, 80645637, 103771031, 113477569, 131317187, 134338119, 134977200, 135812413, 137003910, 152034576, 160964199, 163413438, 178103529, 179323785, 184553402, 196396343, 198955020, 223558121, 226395419, 250112314, 251887757, 252159088
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| ChEBI ID |
CHEBI:34838
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6947). | |||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 3 | Endocrinological and pathological effects of anabolic-androgenic steroid in male rats. Endocr J. 2004 Aug;51(4):425-34. | |||
| REF 4 | Effects of 5-fluorouracil and 2 alpha-methyldihydrotestosterone propionate on the growth of human breast carcinoma MCF-7 in vitro. Eur J Cancer Clin Oncol. 1983 Sep;19(9):1231-7. | |||
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