Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09MGR
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| Former ID |
DAP000738
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| Drug Name |
Etoricoxib
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| Synonyms |
Algix; Arcoxia; Etoricoxibe; Nucoxia; Tauxib; L791456; MK 0663; MK 663; Algix (TN); Arcoxia (TN); L-791456; MK-0663; MK-663; Merck Sharp & Dohme brand of etoricoxib; Tauxib (TN); Etoricoxib (USAN/INN); Etoricoxib [USAN:INN:BAN]; 5-Chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine; 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine; 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine; 5CH
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| Drug Type |
Small molecular drug
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| Indication | Rheumatoid arthritis [ICD-11: FA20] | Approved | [1], [2] | |
| Therapeutic Class |
Antiinflammatory Agents
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| Company |
Merck & Co
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H15ClN2O2S
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| Canonical SMILES |
CC1=NC=C(C=C1)C2=C(C=C(C=N2)Cl)C3=CC=C(C=C3)S(=O)(=O)C
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| InChI |
1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3
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| InChIKey |
MNJVRJDLRVPLFE-UHFFFAOYSA-N
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| CAS Number |
CAS 202409-33-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
13883, 6613371, 7979618, 10240801, 12015199, 14828179, 17397801, 26758000, 29303851, 46504505, 49655565, 50065687, 57340488, 58108264, 76715678, 79356674, 85209827, 92309001, 99214846, 99437360, 99443637, 103169851, 103853298, 103965754, 104418927, 118048491, 125536726, 126645211, 126671483, 128620771, 134338025, 135079337, 137001913, 142355996, 144205759, 160964864, 162188900, 163123240, 163414197, 163620860, 163686187, 163849037, 164787972, 170465621, 171579232, 175266728, 175611945, 176484244, 177749312, 178100245
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| ChEBI ID |
CHEBI:6339
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| ADReCS Drug ID | BADD_D00856 | |||
| SuperDrug ATC ID |
M01AH05
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| SuperDrug CAS ID |
cas=202409334
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2896). | |||
| REF 2 | Emerging analgesics in cancer pain management. Expert Opin Emerg Drugs. 2005 Feb;10(1):151-71. | |||
| REF 3 | The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study. J Orthop Surg Res. 2009 May 26;4:17. | |||
| REF 4 | Antiinflammatory effects of etoricoxib alone and combined with NSAIDs in LPS-induced reactive arthritis. Inflamm Res. 2008 Dec;57(12):586-92. | |||
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