Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09CZV
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| Former ID |
DNC002610
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| Drug Name |
Methyl Mercury Ion
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| Synonyms |
Methylmercury(1+); Methylmercury II; Methyl Mercury Ion; Methylmercury ion; Methyl mercury; METHYLMERCURY(II) CATION; Monomethylmercury cation; Methylmercury ion(1+); CH3Hg+; Mercury(1+), methyl-; 22967-92-6; methylmercury(II); AC1L1NGS; Methyl mercury(II) cation; CH3Hg(+); [HgMe](+); Mercury(1+), methyl-, ion; DTXSID9024198; [HgCH3](+); CTK8D8906; HSDB 3930; CHEBI:49747; AKOS015903545; BRN 3902999; LS-89823; C18672; I14-18601; I14-114322
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
CH3Hg+
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| Canonical SMILES |
C[Hg+]
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| InChI |
1S/CH3.Hg/h1H3;/q;+1
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| InChIKey |
DBUXSCUEGJMZAE-UHFFFAOYSA-N
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| CAS Number |
CAS 22967-92-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:49747
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| Interaction between the Drug and Microbe | Top | |||
|---|---|---|---|---|
| The Metabolism of Drug Affected by Studied Microbe(s) | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Gut microbiota | ||||
| Studied Microbe: Gut microbiota unspecific | [2], [3] | |||
| Resulting Metabolite | Inorganic mercury | |||
| Metabolic Effect | Decrease toxicity | |||
| Description | Methylmercury can be metabolized to Inorganic mercury by gut microbiota, which results in the decrease of the drug's toxicity. | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
| REF 2 | Metabolism of methylmercuric chloride by the gastro-intestinal flora of the rat. Xenobiotica. 1978 Jan;8(1):37-43. | |||
| REF 3 | Chemical transformation of xenobiotics by the human gut microbiota. Science. 2017 Jun 23;356(6344):eaag2770. | |||
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