Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08CNP
|
|||
| Former ID |
DNCL002110
|
|||
| Drug Name |
AC430
|
|||
| Synonyms |
152-97-6; SCHEMBL11862489; ZINC21981448; AKOS025402073
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | leukaemia [ICD-11: 2A60-2B33; ICD-9: 208.9] | Phase 1 | [1] | |
| Company |
Ambit Biosciences
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H16FN5O
|
|||
| Canonical SMILES |
CC1=CC(=NN1)NC2=NC(=NC3=CC=CC=C32)C(C4=CC=C(C=C4)F)O
|
|||
| InChI |
1S/C19H16FN5O/c1-11-10-16(25-24-11)22-18-14-4-2-3-5-15(14)21-19(23-18)17(26)12-6-8-13(20)9-7-12/h2-10,17,26H,1H3,(H2,21,22,23,24,25)
|
|||
| InChIKey |
DCRWIATZWHLIPN-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 1241914-87-3
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01287858) Study to Assess Safety, Tolerability, and Pharmacokinetics of Oral Doses for AC430 in Healthy Subjects. U.S. National Institutes of Health. | |||
| REF 2 | Selective JAK inhibitors in development for rheumatoid arthritis. Expert Opin Investig Drugs. 2014 Aug;23(8):1067-77. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.