Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07BYK
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| Former ID |
DAP000488
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| Drug Name |
Penciclovir
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| Synonyms |
penciclovir; 39809-25-1; Denavir; Penciclovirum; Vectavir; Penciclovirum [INN-Latin]; Pencyclovir; BRL-39123; BRL 39123; Penciclovir [USAN:INN:BAN]; Penciceovir; UNII-359HUE8FJC; CCRIS 9213; PE2
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Approved | [1], [2] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C10H15N5O3
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| Canonical SMILES |
C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
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| InChI |
1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)2-1-6(3-16)4-17/h5-6,16-17H,1-4H2,(H3,11,13,14,18)
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| InChIKey |
JNTOCHDNEULJHD-UHFFFAOYSA-N
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| CAS Number |
CAS 39809-25-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9621, 626312, 5433020, 7784770, 7889775, 7980269, 8152897, 12013576, 14774399, 15122289, 26719824, 26758052, 26759330, 29223811, 46386598, 46504797, 46506498, 47207082, 49681570, 50028164, 53800602, 57322416, 58107003, 76356225, 85246619, 91615544, 92308296, 92309147, 92710506, 103158227, 103567639, 104307247, 118046008, 118314778, 124658988, 124799997, 125349760, 126631814, 126658134, 126664331, 128301646, 131313494, 134213303, 134222457, 134337781, 135030805, 135260574, 137005929, 137035478, 141089745
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| ChEBI ID |
CHEBI:7956
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| ADReCS Drug ID | BADD_D01708 | |||
| SuperDrug ATC ID |
D06BB06; J05AB13
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| SuperDrug CAS ID |
cas=039809251
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Herpes simplex virus DNA polymerase UL30 (HSV UL30) | Target Info | Inhibitor | [3] |
| Thymidine kinase 1 (TK1) | Target Info | Inhibitor | [4] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | Antimicrobial strategies: inhibition of viral polymerases by 3'-hydroxyl nucleosides. Drugs. 2009;69(2):151-66. | |||
| REF 4 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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