Drug Information
Drug General Information | Top | |||
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Drug ID |
D06NVJ
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Former ID |
DAP001410
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Drug Name |
Nicotinamide
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Synonyms |
Aminicotin; Amixicotyn; Amnicotin; Benicot; Dipegyl; Endobion; Enduramide; Hansamid; Mediatric; Niacevit; Niacinamide; Niacotinamide; Niamide; Nicamina; Nicamindon; Nicasir; Nicobion; Nicofort; Nicogen; Nicomidol; Nicosylamide; Nicota; Nicotamide; Nicotilamide; Nicotililamido; Nicotinamid; Nicotinamida; Nicotinamidum; Nicotinsaeureamid; Nicotinsaureamid; Nicotol; Nicotylamide; Nicotylamidum; Nicovit; Nicovitina; Nicovitol; Nicozymin; Nikasan; Nikazan; Nikotinamid; Nikotinsaeureamid; Niocinamide; Niozymin; Papulex; Pelmin; Pelmine; Savacotyl; Amid kyseliny nikotinove; Amid kyseliny nikotinove [Czech]; Amide PP; Astra Brand of Niacinamide; Austrovit PP; Delonin amide; Factor pp; Inovitan PP; Jenapharm Brand of Niacinamide; Merck Brand of Niacinamide; Niacinamide Astra Brand; Niacinamide Jenapharm Brand; Niacinamide Merck Brand; Niacinamide Pharmagenix Brand; Niacinamide [USAN]; Niavit PP; Nicotine acid amide; Nicotine amide; Nicotinic acid amide; Nicotinic amide; Nicotinsaureamid Jenapharm; Nicotinsaureamid [German]; Nikotinsaeureamid [German]; Pelonin amide; Pharmagenix Brand of Niacinamide; Vitamin B; Vitamin PP; Witamina PP; Nicosan 2; Vitamin H1; B 3, Vitamin; B3, Vitamin; Beta-Pyridinecarboxamide; Jenapharm, Nicotinsaureamid; Nandervit-N; Niacin-Vitamin B3; Niacinamide (USP); Nicotinamida [INN-Spanish]; Nicotinamide (Niacinamide); Nicotinamidum [INN-Latin]; Niko-tamin; PP-Faktor; Vi-Nicotyl; Vitamin B (VAN); M-(Aminocarbonyl)pyridine; Niacinamide, Nicotinic acid amide, Nicotinamide; Nicotinamide (JP15/INN); Nicotinamide, niacin, vitamin B3; Nicotinamide-carbonyl-14C; Pyridine-3-carboxamide; Pyridine-3-carboxylic acid amide; 3 Pyridinecarboxamide; 3-Carbamoylpyridine; 3-Pyridinecarboxamide; 3-Pyridinecarboxylic acid amide
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Drug Type |
Small molecular drug
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Indication | Inflammatory skin condition [ICD-11: EF20.Y] | Approved | [1], [2] | |
Therapeutic Class |
Antiinflammatory Agents
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Structure |
Download2D MOL |
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Formula |
C6H6N2O
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Canonical SMILES |
C1=CC(=CN=C1)C(=O)N
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InChI |
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
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InChIKey |
DFPAKSUCGFBDDF-UHFFFAOYSA-N
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CAS Number |
CAS 98-92-0
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PubChem Compound ID | ||||
PubChem Substance ID |
3552, 442239, 603582, 820072, 822608, 822612, 822614, 823496, 823501, 823504, 823505, 825387, 825389, 825391, 836760, 839469, 841416, 3134021, 5010821, 7847117, 7889415, 7980123, 8012057, 8012060, 8013436, 8028590, 8139875, 8143743, 8149442, 8150876, 10528901, 11112153, 11335870, 11361109, 11363957, 11366519, 11369081, 11371669, 11374448, 11377243, 11405436, 11462081, 11466909, 11468029, 11483747, 11486617, 11487822, 11490331, 11492780, 11494877
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ChEBI ID |
CHEBI:17154
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SuperDrug ATC ID |
A11HA01
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SuperDrug CAS ID |
cas=000051127
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Target and Pathway | Top | |||
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Target(s) | Poly [ADP-ribose] polymerase 1 (PARP1) | Target Info | Binder | [3] |
KEGG Pathway | Base excision repair | |||
NF-kappa B signaling pathway | ||||
Panther Pathway | FAS signaling pathway | |||
Pathway Interaction Database | Integrin-linked kinase signaling | |||
Caspase Cascade in Apoptosis | ||||
Notch-mediated HES/HEY network | ||||
Reactome | Dual Incision in GG-NER | |||
WikiPathways | FAS pathway and Stress induction of HSP regulation | |||
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | ||||
Nanoparticle triggered regulated necrosis | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1588). | |||
REF 2 | Drug information of Nicotinamide. United States Environmental Protection Agency. 2015 | |||
REF 3 | beta-1,2,3-Triazolyl-nucleosides as nicotinamide riboside mimics. Nucleosides Nucleotides Nucleic Acids. 2009 Mar;28(3):238-59. |
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